Droplet-Aware Module-Based Synthesis for Fault-Tolerant Digital Microfluidic Biochips

Elena Maftei, Paul Pop, Jan Madsen

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    Microfluidic biochips are replacing the conventional biochemical analyzers, and are able to integrate on-chip all the basic functions for biochemical analysis. On a “digital” biochip liquids are manipulated as discrete droplets on a two-dimensional microfluidic array of electrodes. Basic operations, such as mixing and dilution, are performed on the array, by routing the corresponding droplets on a group of electrodes, forming a virtual device. Initially researchers have ignored the locations of droplets during operation execution, and have considered that all electrodes inside devices are occupied.We have recently proposed a droplet-aware approach for the execution of operations on the microfluidic array, in which the locations of droplets inside devices are known at each time step. In this article we extend the droplet-aware approach to consider the synthesis of biochips which contain defective electrodes on the microfluidic array. We show that for such biochips knowing the exact locations of droplets during operation execution leads to significant improvements in the completion time of applications.
    Original languageEnglish
    Title of host publication2012 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP)
    PublisherIEEE
    Publication date2012
    Pages47-52
    ISBN (Print)978-1-4673-0785-7
    Publication statusPublished - 2012
    Event2012 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP) - Cannes Côte d'Azur, France
    Duration: 25 Apr 201227 Apr 2012
    http://cmp.imag.fr/Conferences/dtip/dtip2012/

    Conference

    Conference2012 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP)
    CountryFrance
    CityCannes Côte d'Azur
    Period25/04/201227/04/2012
    Internet address

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