Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria

Research output: Contribution to journalJournal article – Annual report year: 2017Researchpeer-review

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  • Author: Crofts, Terence S.

    Washington University St. Louis, United States

  • Author: Wang, Bin

    Washington University St. Louis, United States

  • Author: Spivak, Aaron

    Washington University St. Louis, United States

  • Author: Gianoulis, Tara A.

    Harvard University, United States

  • Author: Forsberg, Kevin J.

    Washington University St. Louis, United States

  • Author: Gibson, Molly K.

    Washington University St. Louis, United States

  • Author: Johnsky, Lauren A.

    Edgewood Chemical Biological Center, United States

  • Author: Broomall, Stacey M.

    Edgewood Chemical Biological Center, United States

  • Author: Rosenzweig, C. Nicole

    Edgewood Chemical Biological Center, United States

  • Author: Skowronski, Evan W.

    Edgewood Chemical Biological Center, United States

  • Author: Gibbons, Henry S.

    Edgewood Chemical Biological Center, United States

  • Author: Sommer, Morten Otto Alexander

    Bacterial Synthetic Biology, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800, Kgs. Lyngby, Denmark

  • Author: Dantas, Gautam

    Washington University St. Louis, United States

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Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic.
Original languageEnglish
Article numbere00653-17
JournalGenome Announcements
Volume5
Issue number32
Number of pages3
ISSN2169-8287
DOIs
Publication statusPublished - 2017

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This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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