Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field

Morten Bang Jensen; Peter Balling; Simon J. Doran; Jørgen B.B. Petersen; Isak H. Wahlstedt; Ludvig P. Muren

doi:10.1016/j.phro.2020.10.003

Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field

Morten Bang Jensen^*
, Peter Balling
, Simon J. Doran
, Jørgen B.B. Petersen
, Isak H. Wahlstedt
, Ludvig P. Muren

^*Corresponding author for this work

Department of Health Technology

Aarhus University Hospital
Aarhus University
Institute of Cancer Research

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery.

Original language	English
Journal	Physics and Imaging in Radiation Oncology
Volume	16
Pages (from-to)	81-84
ISSN	2405-6316
DOIs	https://doi.org/10.1016/j.phro.2020.10.003
Publication status	Published - 2020

Keywords

3D radiation dosimetry
Magnetic resonance imaging guided radiotherapy

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10.1016/j.phro.2020.10.003

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title = "Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field",

abstract = "The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery.",

keywords = "3D radiation dosimetry, Magnetic resonance imaging guided radiotherapy",

author = "Jensen, \{Morten Bang\} and Peter Balling and Doran, \{Simon J.\} and Petersen, \{J{\o}rgen B.B.\} and Wahlstedt, \{Isak H.\} and Muren, \{Ludvig P.\}",

year = "2020",

doi = "10.1016/j.phro.2020.10.003",

language = "English",

volume = "16",

pages = "81--84",

journal = "Physics and Imaging in Radiation Oncology",

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TY - JOUR

T1 - Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field

AU - Jensen, Morten Bang

AU - Balling, Peter

AU - Doran, Simon J.

AU - Petersen, Jørgen B.B.

AU - Wahlstedt, Isak H.

AU - Muren, Ludvig P.

PY - 2020

Y1 - 2020

N2 - The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery.

AB - The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery.

KW - 3D radiation dosimetry

KW - Magnetic resonance imaging guided radiotherapy

U2 - 10.1016/j.phro.2020.10.003

DO - 10.1016/j.phro.2020.10.003

M3 - Journal article

C2 - 33458348

SN - 2405-6316

VL - 16

SP - 81

EP - 84

JO - Physics and Imaging in Radiation Oncology

JF - Physics and Imaging in Radiation Oncology

ER -

Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field

Abstract

Keywords

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