Does RF spoiling enhance human in-vivo brain MR Current Density Imaging (MRCDI)?

Cihan Göksu, Lars G. Hanson, Hartwig R. Siebner, Philipp Ehses, Klaus Scheffler, Axel Thielscher

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review


MRCDI is an emerging modality for non-invasive measurement of weak currents in the human brain, which is important in several neuroscientific applications. It is based on current-induced field measurements and requires high sensitivity to the extrinsic field changes. Measurement sensitivity can be compromised by irrelevant field changes caused by physiological variation. Here, we compare the performance of the so far most sensitive MRCDI method based on steady-state free precession free induction decay (SSFP-FID) with its RF-spoiled counterpart fast low angle shot (FLASH). No significant sensitivity differences were observed in slices covering the upper part of the brain, but
SSFP-FID had ~20% lower noise floors in lower slices. For the relevant acquisition parameters, FLASH exhibits no remarkable image quality enhancements in 2D.
Original languageEnglish
Publication date2019
Number of pages3
Publication statusPublished - 2019
EventISMRM 27th Annual Meeting & Exhibition - Palais des congrès de Montréal, Montréal, Canada
Duration: 11 May 201916 May 2019


ConferenceISMRM 27th Annual Meeting & Exhibition
LocationPalais des congrès de Montréal
Internet address

Bibliographical note

Abstract from ISMRM 27th Annual Meeting & Exhibition, Montréal, Canada, 2019


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