Dna origami beads for fluorescence quantification in microfluidics

Denis Selnihhin; Jens Bæk Simonsen; Finn Skou Pedersen

Dna origami beads for fluorescence quantification in microfluidics

Denis Selnihhin (Inventor), Jens Bæk Simonsen (Inventor), Finn Skou Pedersen (Inventor)

Department of Health Technology

Research output: Patent

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Abstract

A method is provided for calibrating a microfluidic system comprising, which method is based on using beads having a structure based on DNA origami, wherein said structure comprises a predetermined number of fluorophores. Furthermore, methods for determining the level of an antigen using microfluidics calibrated using fluorescent microbeads as provided herein. Also, methods are provided for determining the presence or state of a haematological disease by calibrated a microfluidics system.

Original language	English
IPC	G01N 33/ 58 A I
Patent number	WO2019149932
Filing date	02/02/2018
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	02/02/2018
Priority number	EP20180154868
Publication status	Published - 8 Aug 2019

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title = "Dna origami beads for fluorescence quantification in microfluidics",

abstract = "A method is provided for calibrating a microfluidic system comprising, which method is based on using beads having a structure based on DNA origami, wherein said structure comprises a predetermined number of fluorophores. Furthermore, methods for determining the level of an antigen using microfluidics calibrated using fluorescent microbeads as provided herein. Also, methods are provided for determining the presence or state of a haematological disease by calibrated a microfluidics system.",

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AU - Selnihhin, Denis

AU - Simonsen, Jens Bæk

AU - Pedersen, Finn Skou

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N2 - A method is provided for calibrating a microfluidic system comprising, which method is based on using beads having a structure based on DNA origami, wherein said structure comprises a predetermined number of fluorophores. Furthermore, methods for determining the level of an antigen using microfluidics calibrated using fluorescent microbeads as provided herein. Also, methods are provided for determining the presence or state of a haematological disease by calibrated a microfluidics system.

AB - A method is provided for calibrating a microfluidic system comprising, which method is based on using beads having a structure based on DNA origami, wherein said structure comprises a predetermined number of fluorophores. Furthermore, methods for determining the level of an antigen using microfluidics calibrated using fluorescent microbeads as provided herein. Also, methods are provided for determining the presence or state of a haematological disease by calibrated a microfluidics system.

M3 - Patent

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Dna origami beads for fluorescence quantification in microfluidics

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