Distribution of vitamins A (retinol) and E (alpha-tocopherol) in polar bear kidney: Implications for biomarker studies

T.Ø. Bechshøft, Jette Jakobsen, C. Sonne, R. Dietz

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Vitamins A and E content of inner organs, among these the kidneys, are increasingly being used as an indicator of adverse effects caused to the organism by e.g. environmental contaminants. In general, only a renal sub sample is used for analyses, and it is thus essential to know which part of the organ to sample in order to get a representative value for this important biomarker. The aim here was to assess the distribution of vitamins A (retinol) and E (α-tocopherol) within the polar bear multireniculate kidney (i.e. polar vs. medial position) and also within the cortex vs. medulla of each separate renculi. The results showed no significant difference between the medial and polar renculi with regards to either retinol (p=0.44) or α-tocopherol (p=0.75). There were, however, significant differences between cortex and medulla for both vitamins (retinol, p=0.0003; α-tocopherol, p
Original languageEnglish
JournalScience of the Total Environment
Volume409
Issue number18
Pages (from-to)3508-3511
ISSN0048-9697
DOIs
Publication statusPublished - 2011

Keywords

  • Retinol
  • Vitamin
  • Renculi
  • Kidney
  • Ursus maritimus
  • Tocopherol

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