Dissacharide formulations for controlled drug release

Thomas Lars Andresen (Inventor), Jonas Rosager Henriksen (Inventor), Anders Elias Hansen (Inventor), Carl Fredrik Melander (Inventor), Elizabeth Serrano Chávez (Inventor), Linda Maria Bruun (Inventor)

Research output: Patent

339 Downloads (Pure)

Abstract

The present invention relates to a composition comprising non-water soluble dissacharides and oil, a solvent and at least one pharmaceutical ingredient, wherein the composition contains at least two compounds selected from saccharides and lipid oils such as lactose octabenzoate Methyl hepta-O-isobutyryl-α,β-lactoside, α,β-Lactose octa para-iodobenzoate, 3-iodobenzyl hepta-O-isobutyryl-α,β-lactoside, lactose octapropionate, lactose octaisobutyrate, sucrose octabenzoate, glycerol trihexanoate, Glycerol trioctanoate, Glycerol tridecanoate, Lipiodol, ethyl myristate, ethyl palmitate, ethyl oleoate and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 2,000 centipoise (cP) after administration.

Original languageEnglish
IPCA61K 47/ 24 A I
Patent numberWO2020249801
Filing date12/07/2020
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date12/06/2019
Priority numberSE20190050699
Publication statusPublished - 17 Dec 2020

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