We describe a novel dispersive solid-phase imprinting technique for the production of nano-sized molecularly imprinted polymers (nanoMIPs) as plastic antibodies. The template was immobilized on in-house synthesized magnetic microspheres instead of conventional glass beads. As a result, high-affinity and template-free MIPs were produced in higher yields.
Ashley, J., Feng, X., Halder, A., Zhou, T., & Sun, Y. (2018). Dispersive solid-phase imprinting of proteins for the production of plastic antibodies. Chemical Communications, 54(27), 3355-3358. https://doi.org/10.1039/c8cc00343b