Discovery and optimization of peptide-based anti-cobratoxins

M. Sola , Andreas Hougaard Laustsen, J. Johannesen, T. Lynagh, Mads Hartvig Clausen, B. Lohse

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More than 5.5 million people per year are victims of snake envenomation, resulting in 125,000 deaths and 400,000amputations worldwide. Antivenoms are still produced by animal immunization procedures, and they areassociated with a high risk of severe adverse reactions. Alternatively, synthetic peptides may open the possibility for newtherapies with better efficacy and safety. Here, we report the discovery and optimization of a synthetic peptide directedagainst α-cobratoxin (α-CTX), the most toxic component of Monocled cobra (Naja kaouthia).
Original languageEnglish
Publication date2015
Number of pages1
Publication statusPublished - 2015
EventSymposium for Biological and Life Science Students (SymBLS) 2015 - Cambridge, United Kingdom
Duration: 6 Nov 20156 Nov 2015


ConferenceSymposium for Biological and Life Science Students (SymBLS) 2015
Country/TerritoryUnited Kingdom


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