More than 5.5 million people per year are victims of snake envenomation, resulting in 125,000 deaths and 400,000amputations worldwide. Antivenoms are still produced by animal immunization procedures, and they areassociated with a high risk of severe adverse reactions. Alternatively, synthetic peptides may open the possibility for newtherapies with better efficacy and safety. Here, we report the discovery and optimization of a synthetic peptide directedagainst α-cobratoxin (α-CTX), the most toxic component of Monocled cobra (Naja kaouthia).
|Number of pages||1|
|Publication status||Published - 2015|
|Event||Symposium for Biological and Life Science Students (SymBLS) 2015 - Cambridge, United Kingdom|
Duration: 6 Nov 2015 → 6 Nov 2015
|Conference||Symposium for Biological and Life Science Students (SymBLS) 2015|
|Period||06/11/2015 → 06/11/2015|
Sola , M., Laustsen, A. H., Johannesen, J., Lynagh, T., Clausen, M. H., & Lohse, B. (2015). Discovery and optimization of peptide-based anti-cobratoxins. Poster session presented at Symposium for Biological and Life Science Students (SymBLS) 2015, Cambridge, United Kingdom.