Abstract
The HIV viruses infect cells by endocytosis and takes over parts of the cells reaction pathways in order to reproduce itself and spread the infection. One such pathway is the mammalian inflammatory signaling, which invoke NF-κB as the principal transcription factor. A treatment against HIV could be based on blocking the NF-κB pathway by a suitably designed drug. The aim of the current project is to investigate the feasibility of this idea by using mathematical modelling of the NF-κB pathway.
Original language | English |
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Publication date | 2008 |
Publication status | Published - 2008 |
Event | 2008 Fields-MITACS Industrial Problem-Solving Workshop - University of Toronto, Fields Institute, 222 College Street, Toronto, Canada Duration: 11 Aug 2008 → 15 Aug 2008 |
Workshop
Workshop | 2008 Fields-MITACS Industrial Problem-Solving Workshop |
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Location | University of Toronto, Fields Institute, 222 College Street |
Country/Territory | Canada |
City | Toronto |
Period | 11/08/2008 → 15/08/2008 |
Keywords
- HIV therapies
- Nonlinear models of bio systems
- Inflamatory pathway