Direct electrochemical enzyme electron transfer on electrodes modified by self-assembled molecular monolayers

Xiaomei Yan*, Jing Tang, David Ackland Tanner, Jens Ulstrup, Xinxin Xiao

*Corresponding author for this work

Research output: Contribution to journalReviewpeer-review

12 Downloads (Pure)

Abstract

Self-assembled molecular monolayers (SAMs) have long been recognized as crucial “bridges” between redox enzymes and solid electrode surfaces, on which the enzymes undergo direct electron transfer (DET)—for example, in enzymatic biofuel cells (EBFCs) and biosensors. SAMs possess a wide range of terminal groups that enable productive enzyme adsorption and fine-tuning in favorable orientations on the electrode. The tunneling distance and SAM chain length, and the contacting terminal SAM groups, are the most significant controlling factors in DET-type bioelectrocatalysis. In particular, SAM-modified nanostructured electrode materials have recently been extensively explored to improve the catalytic activity and stability of redox proteins immobilized on electrochemical surfaces. In this report, we present an overview of recent investigations of electrochemical enzyme DET processes on SAMs with a focus on single-crystal and nanoporous gold electrodes. Specifically, we consider the preparation and characterization methods of SAMs, as well as SAM applications in promoting interfacial electrochemical electron transfer of redox proteins and enzymes. The strategic selection of SAMs to accord with the properties of the core redox protein/enzymes is also highlighted.
Original languageEnglish
Article number1458
JournalCatalysts
Volume10
Issue number12
Number of pages26
ISSN2073-4344
DOIs
Publication statusPublished - 2020

Fingerprint Dive into the research topics of 'Direct electrochemical enzyme electron transfer on electrodes modified by self-assembled molecular monolayers'. Together they form a unique fingerprint.

Cite this