Activities per year
Abstract
Candidemia and invasive candidiasis is a cause of high mortality and morbidity rates among hospitalized patients worldwide. The occurrence of the infections increases due to the complexity of the patients and overuse of the antifungal therapy. The current Candida detection method includes blood culturing which is a lengthy procedure and thus delays the administration of the antifungal therapy. Even though the results are available after 48 h it is still the gold standard in pathogen detection in a hospital setting. In this work we present an electrochemical impedance sensor that is capable of detecting Candida albicans yeast. The yeast cells are captured on electrodes specifically functionalized with anti-Candida antibodies and detection is achieved by electrochemical impedance spectroscopy. The sensor allows for detection of the yeast cells at clinically relevant concentrations in less than 1 h.
Original language | English |
---|---|
Article number | 2214 |
Journal | Sensors |
Volume | 18 |
Issue number | 7 |
ISSN | 1424-8220 |
DOIs | |
Publication status | Published - 2018 |
Keywords
- Candida
- Electrochemical impedance spectroscopy
- Membrane based sensor
Fingerprint
Dive into the research topics of 'Direct detection of candida albicans with a membrane based electrochemical impedance spectroscopy sensor'. Together they form a unique fingerprint.Activities
- 1 Conference presentations
-
An Impedimetric Biosensor for Early Rapid Diagnosis of Invasive Fungal Infections in Critically-ill Patients
Esmail Tehrani, S. (Speaker), Kwasny, D. (Other), Almeida, C. (Other), Schjødt, I. (Other) & Svendsen, W. E. (Other)
3 Jul 2017 → 7 Jul 2017Activity: Talks and presentations › Conference presentations