Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths

Oscar Andrés Prado-Rubio; Wai Fung Hui; Mads Stevnsborg; Manuel Pinelo; Jakob Kjøbsted Huusom

doi:10.1016/B978-0-443-15274-0.50409-1

Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths

Oscar Andrés Prado-Rubio^*, Wai Fung Hui, Mads Stevnsborg, Manuel Pinelo, Jakob Kjøbsted Huusom

^*Corresponding author for this work

Universidad Nacional de Colombia

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

In the near future, tools brought on by digitalization will play a more significant role in technology development and operation for debottlenecking challenges in the biochemical industry. In that regard, a novel vibrating membrane filtration system at pilot scale is currently under investigation to fractionate bio-succinic acid fermentation broth. Remarkably sustained flux has been obtained that is 3.6 times higher than the best results found in literature. Experimental data was used to develop a digital object that combine a robust communication system and hybrid model to predict hydrodynamics and fouling rate. The digital object is used to forecast membrane performance 25 min ahead, predicting the flux with high accuracy (4% error) and the onset of the irreversible fouling formation during step-up experiments. These tools will become the core of a digital twin for the adaptive operation of the ultrafiltration system under uncertainty.

Original language	English
Title of host publication	Proceedings of the 33rd European Symposium on Computer Aided Process Engineering
Editors	Antonis Kokossis, Michael C. Georgiadis, Efstratios N. Pistikopoulos
Volume	52
Publisher	Elsevier
Publication date	2023
Pages	2575-2580
ISBN (Print)	978-0-443-23553-5, 978-0-443-15274-0
DOIs	https://doi.org/10.1016/B978-0-443-15274-0.50409-1
Publication status	Published - 2023
Event	33rd European Symposium on Computer Aided Process Engineering - Athens, Greece Duration: 18 Jun 2023 → 21 Jun 2023

Conference

Conference	33rd European Symposium on Computer Aided Process Engineering
Country/Territory	Greece
City	Athens
Period	18/06/2023 → 21/06/2023

Series	Computer Aided Chemical Engineering
Volume	52
ISSN	1570-7946

Keywords

Digital-twin
Vibrating membrane ultrafiltration
Fractionation fermentation

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10.1016/B978-0-443-15274-0.50409-1

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Prado-Rubio, O. A., Hui, W. F., Stevnsborg, M., Pinelo, M., & Huusom, J. K. (2023). Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths. In A. Kokossis, M. C. Georgiadis, & E. N. Pistikopoulos (Eds.), Proceedings of the 33rd European Symposium on Computer Aided Process Engineering (Vol. 52, pp. 2575-2580). Elsevier. https://doi.org/10.1016/B978-0-443-15274-0.50409-1

Prado-Rubio, Oscar Andrés ; Hui, Wai Fung ; Stevnsborg, Mads et al. / Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths. Proceedings of the 33rd European Symposium on Computer Aided Process Engineering. editor / Antonis Kokossis ; Michael C. Georgiadis ; Efstratios N. Pistikopoulos. Vol. 52 Elsevier, 2023. pp. 2575-2580 (Computer Aided Chemical Engineering, Vol. 52).

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abstract = "In the near future, tools brought on by digitalization will play a more significant role in technology development and operation for debottlenecking challenges in the biochemical industry. In that regard, a novel vibrating membrane filtration system at pilot scale is currently under investigation to fractionate bio-succinic acid fermentation broth. Remarkably sustained flux has been obtained that is 3.6 times higher than the best results found in literature. Experimental data was used to develop a digital object that combine a robust communication system and hybrid model to predict hydrodynamics and fouling rate. The digital object is used to forecast membrane performance 25 min ahead, predicting the flux with high accuracy (4% error) and the onset of the irreversible fouling formation during step-up experiments. These tools will become the core of a digital twin for the adaptive operation of the ultrafiltration system under uncertainty.",

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Prado-Rubio, OA, Hui, WF, Stevnsborg, M, Pinelo, M & Huusom, JK 2023, Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths. in A Kokossis, M C. Georgiadis & E N. Pistikopoulos (eds), Proceedings of the 33rd European Symposium on Computer Aided Process Engineering. vol. 52, Elsevier, Computer Aided Chemical Engineering, vol. 52, pp. 2575-2580, 33rd European Symposium on Computer Aided Process Engineering, Athens, Greece, 18/06/2023. https://doi.org/10.1016/B978-0-443-15274-0.50409-1

Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths. / Prado-Rubio, Oscar Andrés; Hui, Wai Fung; Stevnsborg, Mads et al.
Proceedings of the 33rd European Symposium on Computer Aided Process Engineering. ed. / Antonis Kokossis; Michael C. Georgiadis; Efstratios N. Pistikopoulos. Vol. 52 Elsevier, 2023. p. 2575-2580 (Computer Aided Chemical Engineering, Vol. 52).

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths

AU - Prado-Rubio, Oscar Andrés

AU - Hui, Wai Fung

AU - Stevnsborg, Mads

AU - Pinelo, Manuel

AU - Huusom, Jakob Kjøbsted

PY - 2023

Y1 - 2023

N2 - In the near future, tools brought on by digitalization will play a more significant role in technology development and operation for debottlenecking challenges in the biochemical industry. In that regard, a novel vibrating membrane filtration system at pilot scale is currently under investigation to fractionate bio-succinic acid fermentation broth. Remarkably sustained flux has been obtained that is 3.6 times higher than the best results found in literature. Experimental data was used to develop a digital object that combine a robust communication system and hybrid model to predict hydrodynamics and fouling rate. The digital object is used to forecast membrane performance 25 min ahead, predicting the flux with high accuracy (4% error) and the onset of the irreversible fouling formation during step-up experiments. These tools will become the core of a digital twin for the adaptive operation of the ultrafiltration system under uncertainty.

AB - In the near future, tools brought on by digitalization will play a more significant role in technology development and operation for debottlenecking challenges in the biochemical industry. In that regard, a novel vibrating membrane filtration system at pilot scale is currently under investigation to fractionate bio-succinic acid fermentation broth. Remarkably sustained flux has been obtained that is 3.6 times higher than the best results found in literature. Experimental data was used to develop a digital object that combine a robust communication system and hybrid model to predict hydrodynamics and fouling rate. The digital object is used to forecast membrane performance 25 min ahead, predicting the flux with high accuracy (4% error) and the onset of the irreversible fouling formation during step-up experiments. These tools will become the core of a digital twin for the adaptive operation of the ultrafiltration system under uncertainty.

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KW - Fractionation fermentation

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BT - Proceedings of the 33rd European Symposium on Computer Aided Process Engineering

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PB - Elsevier

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ER -

Prado-Rubio OA, Hui WF, Stevnsborg M, Pinelo M , Huusom JK. Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths. In Kokossis A, C. Georgiadis M, N. Pistikopoulos E, editors, Proceedings of the 33rd European Symposium on Computer Aided Process Engineering. Vol. 52. Elsevier. 2023. p. 2575-2580. (Computer Aided Chemical Engineering, Vol. 52). doi: 10.1016/B978-0-443-15274-0.50409-1

Digital-twin development for a novel vibrating membrane aiming at fractionating fermentation broths

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