Differences in retinoid levels and metabolism among gastropod lineages: Imposex-susceptible gastropods lack the ability to store retinoids in the form of retinyl esters.

Manuel Gesto, L. Filipe C. Castro, Miguel Machado Santos

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Highlights: [•] Until recently, the presence of an elaborated retinoid system was believed to be a chordate/vertebrate novelty. [•] Patella depressa has the capacity to store retinoids in the form of inactive retinyl esters. [•] The imposex-susceptible species Nucella lapillus and Nassarius reticulatus lacked detectable amounts of retinol or retinyl esters. [•] An exposure test with N. lapillus confirmed that this species is not able to synthesize retinyl esters in vivo. [•] The incapacity to inactivate retinoid precursors might negatively affect retinoid signaling homeostasis.
Original languageEnglish
JournalAquatic Toxicology
Volume142-143
Pages (from-to)96-103
ISSN0166-445X
Publication statusPublished - 2013
Externally publishedYes

Keywords

  • RETINOIDS

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