Development of recombinant antivenoms based on mixtures of human antibodies against D. polylepis toxins

Cecilie Knudsen, Mikael Rørdam Andersen, Brian Lohse, Andreas Hougaard Laustsen

    Research output: Contribution to conferencePosterResearchpeer-review

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    Abstract

    With an annual 150,000 deaths and countless amputations and disfigurements,
    snakebite envenoming is an ever-present threat in many parts of the rural tropical
    world1. In sub-Saharan Africa, only 1-2% of victims are treated with antivenom,
    which is currently based on animal-derived antibodies. Due to their heterologous
    origin, antivenoms often provoke serious side effects in human recipients, such as
    serum sickness and anaphylaxis, which in some cases leads to death.
    Original languageEnglish
    Publication date2016
    Number of pages1
    Publication statusPublished - 2016
    EventProtein Interactions Workshop - Technical University of Denmark, Kgs. Lyngby, Denmark
    Duration: 26 Oct 2016 → …

    Workshop

    WorkshopProtein Interactions Workshop
    LocationTechnical University of Denmark
    Country/TerritoryDenmark
    CityKgs. Lyngby
    Period26/10/2016 → …

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