Development of next generation antivenoms based on mixtures of human antibodies

Cecilie Knudsen; Mikael Rørdam Andersen; Robert Harrison; Nicholas Casewell; Andreas Hougaard Laustsen

Development of next generation antivenoms based on mixtures of human antibodies

Cecilie Knudsen, Mikael Rørdam Andersen, Robert Harrison, Nicholas Casewell, Andreas Hougaard Laustsen

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Abstract

With an annual 150,000 deaths and countless amputations and disfigurements,snakebite envenoming is an ever-present threat in many parts of the rural tropicalworld. In sub-Saharan Africa, only 1-2% of victims are treated with antivenom,which is currently based on animal-derived antibodies. Due to their heterologousorigin, antivenoms often provoke serious side effects in human recipients, such asserum sickness and anaphylaxis, which in some cases leads to death.

Original language	English
Publication date	2016
Number of pages	1
Publication status	Published - 2016
Event	Symposium for Biological and Life Science Students 2016 - Cambridge, United Kingdom Duration: 25 Nov 2016 → 25 Nov 2016

Conference

Conference	Symposium for Biological and Life Science Students 2016
Country/Territory	United Kingdom
City	Cambridge
Period	25/11/2016 → 25/11/2016

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SymBLS poster v3 CecilieFinal published version, 1.63 MB

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@conference{32011edf7c174aefb211e982d071959c,

title = "Development of next generation antivenoms based on mixtures of human antibodies",

abstract = "With an annual 150,000 deaths and countless amputations and disfigurements,snakebite envenoming is an ever-present threat in many parts of the rural tropicalworld. In sub-Saharan Africa, only 1-2% of victims are treated with antivenom,which is currently based on animal-derived antibodies. Due to their heterologousorigin, antivenoms often provoke serious side effects in human recipients, such asserum sickness and anaphylaxis, which in some cases leads to death.",

author = "Cecilie Knudsen and Andersen, {Mikael R{\o}rdam} and Robert Harrison and Nicholas Casewell and Laustsen, {Andreas Hougaard}",

year = "2016",

language = "English",

note = "Symposium for Biological and Life Science Students 2016, SymBLS ; Conference date: 25-11-2016 Through 25-11-2016",

}

TY - CONF

T1 - Development of next generation antivenoms based on mixtures of human antibodies

AU - Knudsen, Cecilie

AU - Andersen, Mikael Rørdam

AU - Harrison, Robert

AU - Casewell, Nicholas

AU - Laustsen, Andreas Hougaard

PY - 2016

Y1 - 2016

N2 - With an annual 150,000 deaths and countless amputations and disfigurements,snakebite envenoming is an ever-present threat in many parts of the rural tropicalworld. In sub-Saharan Africa, only 1-2% of victims are treated with antivenom,which is currently based on animal-derived antibodies. Due to their heterologousorigin, antivenoms often provoke serious side effects in human recipients, such asserum sickness and anaphylaxis, which in some cases leads to death.

AB - With an annual 150,000 deaths and countless amputations and disfigurements,snakebite envenoming is an ever-present threat in many parts of the rural tropicalworld. In sub-Saharan Africa, only 1-2% of victims are treated with antivenom,which is currently based on animal-derived antibodies. Due to their heterologousorigin, antivenoms often provoke serious side effects in human recipients, such asserum sickness and anaphylaxis, which in some cases leads to death.

M3 - Poster

T2 - Symposium for Biological and Life Science Students 2016

Y2 - 25 November 2016 through 25 November 2016

ER -

Development of next generation antivenoms based on mixtures of human antibodies

Abstract

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