Development of a microfabricated electrochemical-cantilever hybrid platform

Lee MacKenzie Fischer; Christoffer Pedersen; Karl Elkjær; Nadine-Nicole Noeth; Søren Dohn; Anja Boisen; Maria Tenje

doi:10.1016/j.snb.2011.04.040

Development of a microfabricated electrochemical-cantilever hybrid platform

Lee MacKenzie Fischer, Christoffer Pedersen, Karl Elkjær, Nadine-Nicole Noeth, Søren Dohn, Anja Boisen, Maria Tenje

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

The design and fabrication of a combined electrochemical-cantilever microfluidic system is described. A chip integrating cantilevers with electrodes into a microchannel is presented with the accompanying polymer flow cell. Issues such as electrical and fluid connections are addressed, electromechanical behavior in ionic solution is investigated, and two uses of the system are demonstrated. First, all cantilevers are functionalized with cysteine, to facilitate detection of Cu2+ ions, then one cantilever is electrochemically cleaned in situ to generate a reference cantilever for differential measurements. Two concentrations of Cu2+ ions are successfully measured in this way. Clean cantilevers are used to probe a solution with and without [Fe(CN)6]3−/4− redox couple present, demonstrating the combined voltammetric and deflection readout.

Original language	English
Journal	Sensors and Actuators B: Chemical
Volume	157
Issue number	1
Pages (from-to)	321-327
ISSN	0925-4005
DOIs	https://doi.org/10.1016/j.snb.2011.04.040
Publication status	Published - 2011

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title = "Development of a microfabricated electrochemical-cantilever hybrid platform",

abstract = "The design and fabrication of a combined electrochemical-cantilever microfluidic system is described. A chip integrating cantilevers with electrodes into a microchannel is presented with the accompanying polymer flow cell. Issues such as electrical and fluid connections are addressed, electromechanical behavior in ionic solution is investigated, and two uses of the system are demonstrated. First, all cantilevers are functionalized with cysteine, to facilitate detection of Cu2+ ions, then one cantilever is electrochemically cleaned in situ to generate a reference cantilever for differential measurements. Two concentrations of Cu2+ ions are successfully measured in this way. Clean cantilevers are used to probe a solution with and without [Fe(CN)6]3−/4− redox couple present, demonstrating the combined voltammetric and deflection readout.",

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AU - Fischer, Lee MacKenzie

AU - Pedersen, Christoffer

AU - Elkjær, Karl

AU - Noeth, Nadine-Nicole

AU - Dohn, Søren

AU - Boisen, Anja

AU - Tenje, Maria

PY - 2011

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N2 - The design and fabrication of a combined electrochemical-cantilever microfluidic system is described. A chip integrating cantilevers with electrodes into a microchannel is presented with the accompanying polymer flow cell. Issues such as electrical and fluid connections are addressed, electromechanical behavior in ionic solution is investigated, and two uses of the system are demonstrated. First, all cantilevers are functionalized with cysteine, to facilitate detection of Cu2+ ions, then one cantilever is electrochemically cleaned in situ to generate a reference cantilever for differential measurements. Two concentrations of Cu2+ ions are successfully measured in this way. Clean cantilevers are used to probe a solution with and without [Fe(CN)6]3−/4− redox couple present, demonstrating the combined voltammetric and deflection readout.

AB - The design and fabrication of a combined electrochemical-cantilever microfluidic system is described. A chip integrating cantilevers with electrodes into a microchannel is presented with the accompanying polymer flow cell. Issues such as electrical and fluid connections are addressed, electromechanical behavior in ionic solution is investigated, and two uses of the system are demonstrated. First, all cantilevers are functionalized with cysteine, to facilitate detection of Cu2+ ions, then one cantilever is electrochemically cleaned in situ to generate a reference cantilever for differential measurements. Two concentrations of Cu2+ ions are successfully measured in this way. Clean cantilevers are used to probe a solution with and without [Fe(CN)6]3−/4− redox couple present, demonstrating the combined voltammetric and deflection readout.

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DO - 10.1016/j.snb.2011.04.040

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JO - Sensors and Actuators B: Chemical

JF - Sensors and Actuators B: Chemical

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Development of a microfabricated electrochemical-cantilever hybrid platform

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