Development of a microfabricated electrochemical-cantilever hybrid platform

Lee MacKenzie Fischer, Christoffer Pedersen, Karl Elkjær, Nadine-Nicole Noeth, Søren Dohn, Anja Boisen, Maria Tenje

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    The design and fabrication of a combined electrochemical-cantilever microfluidic system is described. A chip integrating cantilevers with electrodes into a microchannel is presented with the accompanying polymer flow cell. Issues such as electrical and fluid connections are addressed, electromechanical behavior in ionic solution is investigated, and two uses of the system are demonstrated. First, all cantilevers are functionalized with cysteine, to facilitate detection of Cu2+ ions, then one cantilever is electrochemically cleaned in situ to generate a reference cantilever for differential measurements. Two concentrations of Cu2+ ions are successfully measured in this way. Clean cantilevers are used to probe a solution with and without [Fe(CN)6]3−/4− redox couple present, demonstrating the combined voltammetric and deflection readout.
    Original languageEnglish
    JournalSensors and Actuators B: Chemical
    Volume157
    Issue number1
    Pages (from-to)321-327
    ISSN0925-4005
    DOIs
    Publication statusPublished - 2011

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