Optical trapping and manipulation have established a track record for cell handling in small volumes. However, this cell handling capability is often not simultaneously utilized in experiments using other methods for measuring single cell properties such as fluorescent labeling. Such methods often limit the trapping range because of high numerical aperture and imaging requirements. To circumvent these issues, we are developing a BioPhotonics Workstation platform that supports extension modules through a long working distance geometry. Furthermore, a long range axial manipulation range is achieved by the use of counter-propagating beam traps coupled with the long working distance. This geometry provides three dimensional and real time manipulation of a plurality of traps - currently 100 independently reconfigurable - facilitating precise control and a rapid response in all sorts of optical manipulation undertakings. We present ongoing research activities for constructing a compact next generation BioPhotonics Workstation.
|Journal||Proceedings of the SPIE - The International Society for Optical Engineering|
|Publication status||Published - 2011|
|Event||Complex Light and Optical Forces V - San Francisco, CA, United States|
Duration: 26 Jan 2011 → 27 Jan 2011
Conference number: 5
|Conference||Complex Light and Optical Forces V|
|City||San Francisco, CA|
|Period||26/01/2011 → 27/01/2011|
Bibliographical noteCopyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
- Optical manipulation
- Optical correlation
- Generalized Phase Contrast
- Spatial light modulator