Determinants of vitamin D status in a general population of Danish adults

B. Thuesen; L. Husemoen; M. Fenger; Jette Jakobsen; P. Schwarz; U. Toft; L. Ovesen; T. Jørgensen; A. Linneberg

doi:10.1016/j.bone.2011.12.016

Determinants of vitamin D status in a general population of Danish adults

B. Thuesen
, L. Husemoen
, M. Fenger
, Jette Jakobsen
, P. Schwarz
, U. Toft
, L. Ovesen
, T. Jørgensen
, A. Linneberg

National Food Institute

Slagelse Hospital
Copenhagen University Hospital Herlev and Gentofte

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April–September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30–60years participated in a health examination in 1999–2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D

Original language	English
Journal	Bone
Volume	50
Issue number	3
Pages (from-to)	605-610
ISSN	8756-3282
DOIs	https://doi.org/10.1016/j.bone.2011.12.016
Publication status	Published - 2012

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@article{a5cb6894178c4aa8b88d5907372788fe,

title = "Determinants of vitamin D status in a general population of Danish adults",

abstract = "Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April{\textendash}September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30{\textendash}60years participated in a health examination in 1999{\textendash}2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D",

author = "B. Thuesen and L. Husemoen and M. Fenger and Jette Jakobsen and P. Schwarz and U. Toft and L. Ovesen and T. J{\o}rgensen and A. Linneberg",

year = "2012",

doi = "10.1016/j.bone.2011.12.016",

language = "English",

volume = "50",

pages = "605--610",

journal = "Bone",

issn = "8756-3282",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Determinants of vitamin D status in a general population of Danish adults

AU - Thuesen, B.

AU - Husemoen, L.

AU - Fenger, M.

AU - Jakobsen, Jette

AU - Schwarz, P.

AU - Toft, U.

AU - Ovesen, L.

AU - Jørgensen, T.

AU - Linneberg, A.

PY - 2012

Y1 - 2012

N2 - Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April–September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30–60years participated in a health examination in 1999–2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D

AB - Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April–September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30–60years participated in a health examination in 1999–2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D

U2 - 10.1016/j.bone.2011.12.016

DO - 10.1016/j.bone.2011.12.016

M3 - Journal article

SN - 8756-3282

VL - 50

SP - 605

EP - 610

JO - Bone

JF - Bone

IS - 3

ER -

Determinants of vitamin D status in a general population of Danish adults

Abstract

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