Determinants of vitamin D status in a general population of Danish adults

B. Thuesen, L. Husemoen, M. Fenger, Jette Jakobsen, P. Schwarz, U. Toft, L. Ovesen, T. Jørgensen, A. Linneberg

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Abstract

Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April–September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30–60years participated in a health examination in 1999–2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D
Original languageEnglish
JournalBone
Volume50
Issue number3
Pages (from-to)605-610
ISSN8756-3282
DOIs
Publication statusPublished - 2012

Cite this

Thuesen, B., Husemoen, L., Fenger, M., Jakobsen, J., Schwarz, P., Toft, U., Ovesen, L., Jørgensen, T., & Linneberg, A. (2012). Determinants of vitamin D status in a general population of Danish adults. Bone, 50(3), 605-610. https://doi.org/10.1016/j.bone.2011.12.016