Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015

H. Hasman, A. M. Hammerum, F. Hansen, Rene S. Hendriksen, B. Olesen, Yvonne Agersø, Ea Zankari, Pimlapas Leekitcharoenphon, M. Stegger, Rolf Sommer Kaas, Lina Cavaco, D. S. Hansen, Frank Møller Aarestrup, R. L. Skov

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Abstract

The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat. One isolate from chicken meat belonged to the epidemic spreading sequence type ST131. In addition to IncI2*, an incX4 replicon was found to be linked to mcr-1. This report follows a recent detection of mcr-1 in E. coli from animals, food and humans in China.
Original languageEnglish
JournalEurosurveillance (Online Edition)
Volume20
Issue number49
Pages (from-to)1-5
Number of pages5
ISSN1025-496X
DOIs
Publication statusPublished - 2015

Keywords

  • Denmark
  • Escherichia coli
  • antimicrobial resistance
  • bacterial infections
  • clinic
  • healthcare-associated infections
  • molecular methods
  • multidrug resistance
  • surveillance
  • typing

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