Detection of Francisella tularensis in three vole species in Central Europe

Research output: Contribution to journalJournal article – Annual report year: 2019Researchpeer-review

DOI

  • Author: Jeske, Kathrin

    Friedrich-Loeffler-Institute, Germany

  • Author: Tomaso, Herbert

    Friedrich-Loeffler-Institute, Germany

  • Author: Imholt, Christian

    Julius-Kuhn-Institut, Germany

  • Author: Schulz, Jana

    Epidemiology, Division for Diagnostics & Scientific Advice, National Veterinary Institute, Technical University of Denmark, Kemitorvet, 2800, Kgs. Lyngby, Denmark

  • Author: Beerli, Olivia

    Universität Zürich, Switzerland

  • Author: Suchomel, Josef

    Mendel University in Brno, Czech Republic

  • Author: Heroldova, Marta

    Mendel University in Brno, Czech Republic

  • Author: Jacob, Jens

    Julius-Kuhn-Institut, Germany

  • Author: Staubach, Christoph

    Friedrich-Loeffler-Institute, Germany

  • Author: Ulrich, Rainer G.

    Friedrich-Loeffler-Institute, Germany

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Francisella tularensis is a zoonotic, gram-negative bacterium that causes tularemia in humans. Depending on its subspecies and the route of transmission, mild to lethal courses have been reported. F. tularensis subsp. holarctica is the only subspecies found in Europe and affects a plenitude of vertebrates including lagomorphs and rodents. Population outbreaks of certain rodent species are likely to be involved in the transmission of this pathogen. This molecular survey aims to evaluate the presence of F. tularensis in small mammals from three Central European countries. Using a real-time polymerase chain reaction, F. tularensis DNA was detected in common voles (Microtus arvalis) from Switzerland and in field voles (Microtus agrestis) and a bank vole (Myodes glareolus) from Germany, but not in any other small mammal species. All common voles from the Czech Republic were negative for F. tularensis DNA. The prevalence in the three vole species varied between 1.3% and 3.0%. In conclusion, Francisella tularensis DNA was detected in three vole species in two of three countries investigated. The observed low prevalence raises questions on the role of voles for the transmission of Francisella tularensis in Central Europe.
Original languageEnglish
JournalTransboundary and Emerging Diseases
Volume66
Issue number2
Pages (from-to)1029-1032
ISSN1865-1674
DOIs
Publication statusPublished - 2019
CitationsWeb of Science® Times Cited: No match on DOI

    Research areas

  • Bank vole, Common vole, Czech Republic, Field vole, Germany, Switzerland, Tularemia

ID: 160559702