Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform

Onur Durucan; Lidia Morelli; Michael Stenbæk Schmidt; Robert Burger; Tomas Rindzevicius; Anja Boisen

Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform

Onur Durucan, Lidia Morelli, Michael Stenbæk Schmidt, Robert Burger, Tomas Rindzevicius, Anja Boisen

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

In this work we present a novel technology that combines the advantages of centrifugal microfluidics with dynamic in-situ Surface Enhanced Raman Spectroscopy (SERS) sensing. Our technology is based on an automated readout system that allows on-line SERS acquisition on a rotating centrifugal microfluidic platform with embedded gold nanopillar substrates. While spinning, the disc platform enables dynamic SERS acquisition of multiple chips, significantly reducing time-to-result and improving the reproducibility of the acquired spectra, reducing the fluctuation by a factor of 2.

Original language	English
Title of host publication	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Number of pages	3
Publisher	Chemical and Biological Microsystems Society
Publication date	2015
Pages	1831-1833
ISBN (Electronic)	9780979806483
Publication status	Published - 2015
Event	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Hwabaek International Convention Center, Gyeongju-si, Korea, Republic of Duration: 25 Oct 2015 → 29 Oct 2015 Conference number: 19 https://mtas.hdasan.com/

Conference

Conference	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number	19
Location	Hwabaek International Convention Center
Country/Territory	Korea, Republic of
City	Gyeongju-si
Period	25/10/2015 → 29/10/2015
Internet address	https://mtas.hdasan.com/

Keywords

Surface Enhanced Raman Spectroscopy (SERS)
Dynamic SERS
Centrifugal microfluidics

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Durucan, O., Morelli, L., Schmidt, M. S., Burger, R., Rindzevicius, T., & Boisen, A. (2015). Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform. In 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 (pp. 1831-1833). Chemical and Biological Microsystems Society.

Durucan, Onur ; Morelli, Lidia ; Schmidt, Michael Stenbæk et al. / Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015. Chemical and Biological Microsystems Society, 2015. pp. 1831-1833

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title = "Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform",

abstract = "In this work we present a novel technology that combines the advantages of centrifugal microfluidics with dynamic in-situ Surface Enhanced Raman Spectroscopy (SERS) sensing. Our technology is based on an automated readout system that allows on-line SERS acquisition on a rotating centrifugal microfluidic platform with embedded gold nanopillar substrates. While spinning, the disc platform enables dynamic SERS acquisition of multiple chips, significantly reducing time-to-result and improving the reproducibility of the acquired spectra, reducing the fluctuation by a factor of 2.",

keywords = "Surface Enhanced Raman Spectroscopy (SERS), Dynamic SERS, Centrifugal microfluidics",

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year = "2015",

language = "English",

pages = "1831--1833",

booktitle = "19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015",

publisher = "Chemical and Biological Microsystems Society",

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Durucan, O, Morelli, L, Schmidt, MS, Burger, R, Rindzevicius, T & Boisen, A 2015, Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform. in 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015. Chemical and Biological Microsystems Society, pp. 1831-1833, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju-si, Korea, Republic of, 25/10/2015.

Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform. / Durucan, Onur; Morelli, Lidia; Schmidt, Michael Stenbæk et al.
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015. Chemical and Biological Microsystems Society, 2015. p. 1831-1833.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform

AU - Durucan, Onur

AU - Morelli, Lidia

AU - Schmidt, Michael Stenbæk

AU - Burger, Robert

AU - Rindzevicius, Tomas

AU - Boisen, Anja

N1 - Conference code: 19

PY - 2015

Y1 - 2015

N2 - In this work we present a novel technology that combines the advantages of centrifugal microfluidics with dynamic in-situ Surface Enhanced Raman Spectroscopy (SERS) sensing. Our technology is based on an automated readout system that allows on-line SERS acquisition on a rotating centrifugal microfluidic platform with embedded gold nanopillar substrates. While spinning, the disc platform enables dynamic SERS acquisition of multiple chips, significantly reducing time-to-result and improving the reproducibility of the acquired spectra, reducing the fluctuation by a factor of 2.

AB - In this work we present a novel technology that combines the advantages of centrifugal microfluidics with dynamic in-situ Surface Enhanced Raman Spectroscopy (SERS) sensing. Our technology is based on an automated readout system that allows on-line SERS acquisition on a rotating centrifugal microfluidic platform with embedded gold nanopillar substrates. While spinning, the disc platform enables dynamic SERS acquisition of multiple chips, significantly reducing time-to-result and improving the reproducibility of the acquired spectra, reducing the fluctuation by a factor of 2.

KW - Surface Enhanced Raman Spectroscopy (SERS)

KW - Dynamic SERS

KW - Centrifugal microfluidics

M3 - Article in proceedings

SP - 1831

EP - 1833

BT - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015

PB - Chemical and Biological Microsystems Society

T2 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 25 October 2015 through 29 October 2015

ER -

Durucan O, Morelli L, Schmidt MS, Burger R, Rindzevicius T , Boisen A. Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform. In 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015. Chemical and Biological Microsystems Society. 2015. p. 1831-1833

Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform

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Keywords

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