Detection of bacterial metabolites through dynamic acquisition from surface enhanced raman spectroscopy substrates integtrated in a centrifugal microfluidic platform

Onur Durucan, Lidia Morelli, Michael Stenbæk Schmidt, Robert Burger, Tomas Rindzevicius, Anja Boisen

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

In this work we present a novel technology that combines the advantages of centrifugal microfluidics with dynamic in-situ Surface Enhanced Raman Spectroscopy (SERS) sensing. Our technology is based on an automated readout system that allows on-line SERS acquisition on a rotating centrifugal microfluidic platform with embedded gold nanopillar substrates. While spinning, the disc platform enables dynamic SERS acquisition of multiple chips, significantly reducing time-to-result and improving the reproducibility of the acquired spectra, reducing the fluctuation by a factor of 2.
Original languageEnglish
Title of host publication19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Number of pages3
PublisherChemical and Biological Microsystems Society
Publication date2015
Pages1831-1833
ISBN (Electronic)9780979806483
Publication statusPublished - 2015
EventMicroTAS 2015: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Gyeongju, Korea, Republic of
Duration: 25 Oct 201529 Oct 2015
Conference number: 19

Conference

ConferenceMicroTAS 2015
Number19
CountryKorea, Republic of
CityGyeongju
Period25/10/201529/10/2015

Keywords

  • Surface Enhanced Raman Spectroscopy (SERS)
  • Dynamic SERS
  • Centrifugal microfluidics

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