Designing simulation experiments with controllable and uncontrollable factors for applications in healthcare

Christian Dehlendorff, Murat Kulahci, Klaus Kaae Andersen

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    We propose a new methodology for designing computer experiments that was inspired by the split-plot designs that are often used in physical experimentation.The methodology has been developed for a simulation model of a surgical unit in a Danish hospital.We classify the factors as controllable and uncontrollable on the basis of their characteristics in the physical system. The experiments are designed so that, for a given setting of the controllable factors, the various settings of the uncontrollable factors cover the design space uniformly. Moreover the methodology allows for overall uniform coverage in the combined design when all settings of the uncontrollable factors are considered at once.
    Original languageEnglish
    JournalJournal of the Royal Statistical Society, series C (Applied Statistics)
    Volume60
    Issue number1
    Pages (from-to)31-49
    ISSN0952-8385
    DOIs
    Publication statusPublished - 2011

    Keywords

    • Computer experiments
    • Discrete event simulation

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