Design of microfluidic bioreactors using topology optimization

Fridolin Okkels; Henrik Bruus

doi:10.1166/jctn.2007.016

Design of microfluidic bioreactors using topology optimization

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

We address the design of optimal reactors for supporting biological cultures using the method of topology optimization. For some years this method have been used to design various optimal microfluidic devices.1-4 We apply this method to distribute optimally biologic cultures within a flow of nutrition. From this optimized distribution alone the metabolic rate in the reactor increase by close to a factor 20.

Original language	English
Journal	Journal of Computational and Theoretical Nanoscience
Volume	4
Issue number	4
Pages (from-to)	814-816
ISSN	1546-1955
DOIs	https://doi.org/10.1166/jctn.2007.016
Publication status	Published - 2007

Keywords

Microfluidics
Bio-reactors
Topology optimization

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title = "Design of microfluidic bioreactors using topology optimization",

abstract = "We address the design of optimal reactors for supporting biological cultures using the method of topology optimization. For some years this method have been used to design various optimal microfluidic devices.1-4 We apply this method to distribute optimally biologic cultures within a flow of nutrition. From this optimized distribution alone the metabolic rate in the reactor increase by close to a factor 20.",

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AU - Bruus, Henrik

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KW - Microfluidics

KW - Bio-reactors

KW - Topology optimization

U2 - 10.1166/jctn.2007.016

DO - 10.1166/jctn.2007.016

M3 - Journal article

SN - 1546-1955

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JO - Journal of Computational and Theoretical Nanoscience

JF - Journal of Computational and Theoretical Nanoscience

IS - 4

ER -

Design of microfluidic bioreactors using topology optimization

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Keywords

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