Snakebite is one of the world’s most neglected tropical diseases, with an estimated 5 million bites per year, resulting in about 125.000 deaths. The only current treatment for snakebite envenoming is antiserum derived from the blood of immunized mammals(typically horses). These antisera are expensive to produce and carry a high risk of causing hyper-allergic reactions in human recipients due to their heterologous origin. Here we report the discovery of chimeric scFvs against Bothrops asper toxins.
|Number of pages||1|
|Publication status||Published - 2016|
|Event||Symposium for Biological and Life Science Students (SymBLS) 2016 - Cambridge, United Kingdom|
Duration: 25 Nov 2016 → 25 Nov 2016
|Conference||Symposium for Biological and Life Science Students (SymBLS) 2016|
|Period||25/11/2016 → 25/11/2016|
M. Haack, A., B. Hallgren, M., U. W. Friis, R., H. Dam, S., Martos Esteban, A., Andersen, M. R., Kilstrup, M., & Laustsen, A. H. (2016). Design of Fab-based chimeric antibodies against Bothrops asper toxins. Poster session presented at Symposium for Biological and Life Science Students (SymBLS) 2016, Cambridge, United Kingdom.