Design of a quadrature surface coil for hyperpolarized 13C MRS cardiac metabolism studies in pigs

G. Giovannetti, F. Frijia, V. Hartwig, S. Attanasio, L. Menichetti, N. Vanello, V. Positano, Jan Henrik Ardenkjær-Larsen, V. Lionetti, G. D. Aquaro, D. De Marchi, R. F. Schulte, F. Wiesinger, L. Landini, M. Lombardi, M. F. Santarelli

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

This work describes the design of a quadrature surface coil constituted by a circular loop and a butterfly coil, employed in transmit/receive (TX/RX) mode for hyperpolarized 13C studies of pig heart with a clinical 3T scanner. The coil characterization is performed by developing an SNR model for coil performance evaluation in terms of coil resistance, sample-induced resistance and magnetic field pattern. Experimental SNR-vs.-depth profiles, extracted from the [1-13C]acetate phantom chemical shift image (CSI), showed good agreement with the theoretical SNR-vs.-depth profiles. Moreover, the performance of the quadrature coil was compared with the single TX/RX circular and TX/RX butterfly coil, in order to verify the advantage of the proposed configuration over the single coils throughout the volume of interest for cardiac imaging in pig. Finally, the quadrature surface coil was tested by acquiring metabolic maps with hyperpolarized [1-13C]pyruvate injected i.v. in a pig. © 2013 Wiley Periodicals, Inc.
Original languageEnglish
JournalConcepts in Magnetic Resonance. Part B: Magnetic Resonance Engineering (Online)
Volume43
Issue number2
Pages (from-to)69-77
ISSN1552-504X
Publication statusPublished - 2013

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