Dermal uptake of phthalates from clothing: comparison of model to human participant results

Glenn Morrison, Charles J. Weschler, Gabriel Bekö

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Abstract

In this research, we extend a model of transdermal uptake of phthalates to include a layer of clothing. When compared with experimental results, this model better estimates dermal uptake of diethylphthalate (DEP) and di-n-butylphthalate (DnBP) than a previous model. It also demonstrates that uptake is sensitive to both the gap between skin and clothing and the time clothing is allowed to adsorb phthalates. The model predictions are consistent with the observation that exposed clothing increases dermal uptake when compared with uptake observed in bare-skin participants. Extension of this model beyond the cotton-phthalate system will be challenging until data on partition coefficients are quantified for other combinations of SVOCs, fabric materials and environmental conditions.
Original languageEnglish
Title of host publicationProceedings of Indoor Air 2016
Number of pages2
Publication date2016
Article number685
Publication statusPublished - 2016
Event14th international conference on Indoor Air Quality and Climate - Ghent, Belgium
Duration: 3 Jul 20168 Jul 2016
Conference number: 14

Conference

Conference14th international conference on Indoor Air Quality and Climate
Number14
Country/TerritoryBelgium
CityGhent
Period03/07/201608/07/2016

Keywords

  • SVOC
  • Model
  • Fabric
  • Skin
  • Absorption

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