Dermal uptake of phthalates from clothing: comparison of model to human participant results

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    Abstract

    In this research, we extend a model of transdermal uptake of phthalates to include a layer of clothing. When compared with experimental results, this model better estimates dermal uptake of diethylphthalate (DEP) and di-n-butylphthalate (DnBP) than a previous model. It also demonstrates that uptake is sensitive to both the gap between skin and clothing and the time clothing is allowed to adsorb phthalates. The model predictions are consistent with the observation that exposed clothing increases dermal uptake when compared with uptake observed in bare-skin participants. Extension of this model beyond the cotton-phthalate system will be challenging until data on partition coefficients are quantified for other combinations of SVOCs, fabric materials and environmental conditions.
    Original languageEnglish
    Title of host publicationProceedings of Indoor Air 2016
    Number of pages2
    Publication date2016
    Article number685
    Publication statusPublished - 2016
    Event14th international conference on Indoor Air Quality and Climate - Ghent, Belgium
    Duration: 3 Jul 20168 Jul 2016
    Conference number: 14

    Conference

    Conference14th international conference on Indoor Air Quality and Climate
    Number14
    Country/TerritoryBelgium
    CityGhent
    Period03/07/201608/07/2016

    Keywords

    • SVOC
    • Model
    • Fabric
    • Skin
    • Absorption

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