Densities and solubilities of Glycylglycine and Glycyl-L-Alanine in Aqueous Electrolyte Solutions

Martin Peter Breil, Jørgen Mollerup, E. Susanne J. Rudolph, Marcel Ottens, Luuk A. M. van der Wielen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Solubilities of glycylglycine and glycyl-L-alanine in aqueous electrolyte solutions containing 0-6 molal NaCl, 0-1 molal Na2SO4, and 0-1 molal (NH4)(2)SO4, have been determined experimentally at 298.15 K and atmospheric pressure. The solubility of glycylglycine and glycyl-L-alanine in pure water is 1.74 and 4.78 mol/kg of water, respectively. The solubility of glycylglycine in salt solutions of NaCl, Na2SO4, and (NH4)(2)SO4 show a moderate salting-in effect. The solubility of glycyl-L-alanine show a minor or no salting-in effect at low salt concentrations and a moderate salting-out effect at higher salt concentrations in NaCl and Na2SO4, and in (NH4)(2)SO4 the solubility is almost constant. The densities of the solutions have been determined experimentally, and the volume expansions by dissolving salt and dipeptide in water have been calculated. (C) 2003 Elsevier B.V. All rights reserved.
Original languageEnglish
JournalFluid Phase Equilibria
Volume215
Issue number2
Pages (from-to)221-225
ISSN0378-3812
DOIs
Publication statusPublished - 1 Feb 2004

Keywords

  • glycylglycine
  • electrolyte solution
  • dipeptides
  • density
  • solubility

Cite this

Breil, M. P., Mollerup, J., Rudolph, E. S. J., Ottens, M., & van der Wielen, L. A. M. (2004). Densities and solubilities of Glycylglycine and Glycyl-L-Alanine in Aqueous Electrolyte Solutions. Fluid Phase Equilibria, 215(2), 221-225. https://doi.org/10.1016/j.fluid.2003.08.010