DENDRIMER CONJUGATES FOR SELECTIVE OF PROTEIN AGGREGATES

Peter M. H. Heegaard (Inventor), Ulrik Boas (Inventor)

    Research output: Patent

    Abstract

    Dendrimer conjugates are presented, which are formed between a dendrimer and a protein solubilising substance. Such dendrimer conjugates are effective in the treatment of protein aggregate-related diseases (e.g. prion-related diseases). The protein solubilising substance and the dendrimer together show a protein aggregate solubilising effect higher than a physical mixture of the dendrimer and the protein solubilising substance (i.e. a synergistic effect). Such dendrimer conjugates are useful in the treatment or prevention of protein aggregate-relates diseases, in disinfection/decontamination processes and in classifying or identifying protein aggregates. The synthesis of such dendrimer conjugates from readily-available starting materials is described.
    Original languageEnglish
    Patent numberWO2004047869
    Filing date10/06/2004
    CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
    Publication statusPublished - 2004

    Bibliographical note

    International application published under the World Intellectual Property Organization (WIPO)

    Fingerprint Dive into the research topics of 'DENDRIMER CONJUGATES FOR SELECTIVE OF PROTEIN AGGREGATES'. Together they form a unique fingerprint.

    Cite this