Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity

Austin Boesch; Vasily  Rybakin; Nathan  Westcott; Ji Young  Hwang; Kira  Jørgensen; Rasmus  Lassen; Martin  Kræmer; Martin Bak; Gael Veiga; Jonas  Bruun; Carlos  Tassa; Harrison  Rodts; Manny  Sequeira; Glenn  Leary; Santina  Caruso; Becker  Hewes; Jonathan  Fitzgerald; Karsten  Sauer; Thomas  Andresen

Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity

Austin Boesch, Vasily Rybakin, Nathan Westcott, Ji Young Hwang, Kira Jørgensen, Rasmus Lassen, Martin Kræmer, Martin Bak, Gael Veiga, Jonas Bruun, Carlos Tassa, Harrison Rodts, Manny Sequeira, Glenn Leary, Santina Caruso, Becker Hewes, Jonathan Fitzgerald, Karsten Sauer, Thomas Andresen

Department of Health Technology

Torque Therapeutics

Research output: Contribution to conference › Poster › Research › peer-review

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Original language	English
Publication date	2019
Publication status	Published - 2019
Event	34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019) - Gaylord National Hotel & Convention Center, National Harbour, United States Duration: 6 Nov 2019 → 10 Nov 2019 https://www.sitcancer.org/2019/home

Conference

Conference	34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019)
Location	Gaylord National Hotel & Convention Center
Country/Territory	United States
City	National Harbour
Period	06/11/2019 → 10/11/2019
Internet address	https://www.sitcancer.org/2019/home

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Boesch, A., Rybakin, V., Westcott, N., Hwang, J. Y., Jørgensen, K., Lassen, R., Kræmer, M., Bak, M., Veiga, G., Bruun, J., Tassa, C., Rodts, H., Sequeira, M., Leary, G., Caruso, S., Hewes, B., Fitzgerald, J., Sauer, K., & Andresen, T. (2019). Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity. Poster session presented at 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), National Harbour, Maryland, United States.

Boesch, Austin ; Rybakin, Vasily ; Westcott, Nathan et al. / Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity. Poster session presented at 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), National Harbour, Maryland, United States.

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title = "Delivery of TLR7 agonists by Deep-Primed{\texttrademark} T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity",

author = "Austin Boesch and Vasily Rybakin and Nathan Westcott and Hwang, {Ji Young} and Kira J{\o}rgensen and Rasmus Lassen and Martin Kr{\ae}mer and Martin Bak and Gael Veiga and Jonas Bruun and Carlos Tassa and Harrison Rodts and Manny Sequeira and Glenn Leary and Santina Caruso and Becker Hewes and Jonathan Fitzgerald and Karsten Sauer and Thomas Andresen",

year = "2019",

language = "English",

note = "34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), SITC2019 ; Conference date: 06-11-2019 Through 10-11-2019",

url = "https://www.sitcancer.org/2019/home",

}

Boesch, A, Rybakin, V, Westcott, N, Hwang, JY, Jørgensen, K, Lassen, R, Kræmer, M, Bak, M, Veiga, G, Bruun, J, Tassa, C, Rodts, H, Sequeira, M, Leary, G, Caruso, S, Hewes, B, Fitzgerald, J, Sauer, K & Andresen, T 2019, 'Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity', 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), National Harbour, United States, 06/11/2019 - 10/11/2019.

Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity. / Boesch, Austin; Rybakin, Vasily ; Westcott, Nathan et al.
2019. Poster session presented at 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), National Harbour, Maryland, United States.

Research output: Contribution to conference › Poster › Research › peer-review

TY - CONF

T1 - Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity

AU - Boesch, Austin

AU - Rybakin, Vasily

AU - Westcott, Nathan

AU - Hwang, Ji Young

AU - Jørgensen, Kira

AU - Lassen, Rasmus

AU - Kræmer, Martin

AU - Bak, Martin

AU - Veiga, Gael

AU - Bruun, Jonas

AU - Tassa, Carlos

AU - Rodts, Harrison

AU - Sequeira, Manny

AU - Leary, Glenn

AU - Caruso, Santina

AU - Hewes, Becker

AU - Fitzgerald, Jonathan

AU - Sauer, Karsten

AU - Andresen, Thomas

PY - 2019

Y1 - 2019

M3 - Poster

T2 - 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019)

Y2 - 6 November 2019 through 10 November 2019

ER -

Boesch A, Rybakin V, Westcott N, Hwang JY, Jørgensen K, Lassen R et al.. Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity. 2019. Poster session presented at 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), National Harbour, Maryland, United States.