Deep-probe metal-clad waveguide biosensors

Nina Skivesen, Robert Horvath, S. Thinggaard, Niels Bent Larsen, Henrik Chresten Pedersen

    Research output: Contribution to journalJournal articleResearchpeer-review


    Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150-200 nm. The dip-type metal-clad waveguide sensor is shown to be the best all-round alternative to the surface-plasmon resonance biosensor. Both metal-clad waveguides are tested experimentally for cell detection, showing a detection linut of 8-9 cells/mm(2). (c) 2006 Elsevier B.V. All rights reserved.
    Original languageEnglish
    JournalBiosensors and Bioelectronics
    Issue number7
    Pages (from-to)1282-1288
    Publication statusPublished - 2007

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