Abstract
Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150-200 nm. The dip-type metal-clad waveguide sensor is shown to be the best all-round alternative to the surface-plasmon resonance biosensor. Both metal-clad waveguides are tested experimentally for cell detection, showing a detection linut of 8-9 cells/mm(2). (c) 2006 Elsevier B.V. All rights reserved.
Original language | English |
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Journal | Biosensors and Bioelectronics |
Volume | 22 |
Issue number | 7 |
Pages (from-to) | 1282-1288 |
ISSN | 0956-5663 |
DOIs | |
Publication status | Published - 2007 |