COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES

M. H. Jakobsen; Ulrik Boas; E. S. Jauho; Peter M. H. Heegaard

COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES

M. H. Jakobsen (Inventor), Ulrik Boas (Inventor), E. S. Jauho (Inventor), Peter M. H. Heegaard (Inventor)

Research output: Patent

Abstract

The present invention provides a method for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from KDO (2-keto-3-deoxy-D-mannooctonic acid), the method comprising the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM). Comprising a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria

Original language	English
Patent number	WO2000036419
Filing date	22/06/2000
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Publication status	Published - 2000

Bibliographical note

International application published under the World Intellectual Property Organization (WIPO)

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title = "COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES",

abstract = "The present invention provides a method for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from KDO (2-keto-3-deoxy-D-mannooctonic acid), the method comprising the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM). Comprising a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria",

author = "Jakobsen, {M. H.} and Ulrik Boas and Jauho, {E. S.} and Heegaard, {Peter M. H.}",

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TY - PAT

T1 - COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES

AU - Jakobsen, M. H.

AU - Boas, Ulrik

AU - Jauho, E. S.

AU - Heegaard, Peter M. H.

N1 - International application published under the World Intellectual Property Organization (WIPO)

PY - 2000

Y1 - 2000

N2 - The present invention provides a method for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from KDO (2-keto-3-deoxy-D-mannooctonic acid), the method comprising the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM). Comprising a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria

AB - The present invention provides a method for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from KDO (2-keto-3-deoxy-D-mannooctonic acid), the method comprising the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM). Comprising a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria

M3 - Patent

M1 - WO2000036419

Y2 - 2000/06/22

ER -

COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES

Abstract

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