COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES

M. H. Jakobsen (Inventor), Ulrik Boas (Inventor), E. S. Jauho (Inventor), Peter M. H. Heegaard (Inventor)

    Research output: Patent

    Abstract

    The present invention provides a method for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from KDO (2-keto-3-deoxy-D-mannooctonic acid), the method comprising the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM). Comprising a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria
    Original languageEnglish
    Patent numberWO2000036419
    Filing date22/06/2000
    CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
    Publication statusPublished - 2000

    Bibliographical note

    International application published under the World Intellectual Property Organization (WIPO)

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