Abstract
Cultivation of a strain of Penicillium hordei on macerated tulip tissue agar resulted in the stimulated production of a series of four novel hydroxymethyl naphthalene carboxylic acid lactones from the fungus. The naphthalene derivatives were isolated using a combination of vacuum liquid chromatography and preparative HPLC. Their structures were determined by 1D and 2D NMR techniques in conjunction with high-resolution electrospray mass spectrometry (HRESIMS). These metabolites were given the trivial names corymbiferan lactones A-D (1-4).
Original language | English |
---|---|
Journal | Journal of Natural Products |
Volume | 67 |
Pages (from-to) | 1850-1853 |
ISSN | 0163-3864 |
Publication status | Published - 2004 |