Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy

Casper Hyttel Clausen, Gustav Erik Skands, Christian Vinther Bertelsen, Winnie Edith Svendsen

    Research output: Contribution to journal › Journal article › Research › peer-review

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    Abstract

    This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 mu m beads from 1 mu m as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results.
    Original languageEnglish
    JournalMicromachines
    Volume6
    Issue number1
    Pages (from-to)110-120
    Number of pages11
    ISSN2072-666X
    DOIs
    Publication statusPublished - 2015

    Bibliographical note

    Creative Commons Attribution License

    Keywords

    • Electrical impedance spectroscopy
    • Sensitivity
    • Improved design
    • Impedance flow cytometry

    Cite this

    Clausen, Casper Hyttel ; Skands, Gustav Erik ; Bertelsen, Christian Vinther ; Svendsen, Winnie Edith. / Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy. In: Micromachines. 2015 ; Vol. 6, No. 1. pp. 110-120.
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    abstract = "This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 mu m beads from 1 mu m as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results.",
    keywords = "Electrical impedance spectroscopy, Sensitivity, Improved design, Impedance flow cytometry",
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    Clausen, CH, Skands, GE, Bertelsen, CV & Svendsen, WE 2015, 'Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy', Micromachines, vol. 6, no. 1, pp. 110-120. https://doi.org/10.3390/mi6010110

    Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy. / Clausen, Casper Hyttel; Skands, Gustav Erik; Bertelsen, Christian Vinther; Svendsen, Winnie Edith.

    In: Micromachines, Vol. 6, No. 1, 2015, p. 110-120.

    Research output: Contribution to journal › Journal article › Research › peer-review

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    T1 - Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy

    AU - Clausen, Casper Hyttel

    AU - Skands, Gustav Erik

    AU - Bertelsen, Christian Vinther

    AU - Svendsen, Winnie Edith

    N1 - Creative Commons Attribution License

    PY - 2015

    Y1 - 2015

    N2 - This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 mu m beads from 1 mu m as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results.

    AB - This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 mu m beads from 1 mu m as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results.

    KW - Electrical impedance spectroscopy

    KW - Sensitivity

    KW - Improved design

    KW - Impedance flow cytometry

    U2 - 10.3390/mi6010110

    DO - 10.3390/mi6010110

    M3 - Journal article

    VL - 6

    SP - 110

    EP - 120

    JO - Micromachines

    JF - Micromachines

    SN - 2072-666X

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    Clausen CH, Skands GE, Bertelsen CV, Svendsen WE. Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy. Micromachines. 2015;6(1):110-120. https://doi.org/10.3390/mi6010110

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