Construction of the simplest model to explain complex receptor activation kinetics

RP Bywater, A Sorensen, Peter Røgen, Poul G. Hjorth

    Research output: Contribution to journalJournal articleResearchpeer-review


    We study the mathematical solutions to the kinetic equations arising from various simple ligand-reactor models. Focusing on the prediction of the various models for the activity vs. concentration curve, we find that solutions to the kinetic equations arising from the so-called dimer model exibit features observed in some experiments, most noticeably a distinct maximum in the activity curve.
    Original languageEnglish
    JournalJ THEOR BIOL
    Issue number2
    Pages (from-to)139-147
    Publication statusPublished - 2002

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