TY - JOUR
T1 - Consolidating and Exploring Antibiotic Resistance Gene Data Resources
AU - Xavier, Basil Britto
AU - Das, Anupam J.
AU - Cochrane, Guy
AU - De Ganck, Sandra
AU - Kumar-Singh, Samir
AU - Aarestrup, Frank Møller
AU - Goossens, Herman
AU - Malhotra-Kumar, Surbhi
PY - 2016
Y1 - 2016
N2 - The unrestricted use of antibiotics has resulted in rapid acquisition of antibiotic resistance (AR) and spread of multidrug-resistant (MDR) bacterial pathogens. With the advent of next-generation sequencing technologies and their application in understanding MDR pathogen dynamics, it has become imperative to unify AR gene data resources for easy accessibility for researchers. However, due to the absence of a centralized platform for AR gene resources, availability, consistency, and accuracy of information vary considerably across different databases. In this article, we explore existing AR gene data resources in order to make them more visible to the clinical microbiology community, to identify their limitations, and to propose potential solutions.
AB - The unrestricted use of antibiotics has resulted in rapid acquisition of antibiotic resistance (AR) and spread of multidrug-resistant (MDR) bacterial pathogens. With the advent of next-generation sequencing technologies and their application in understanding MDR pathogen dynamics, it has become imperative to unify AR gene data resources for easy accessibility for researchers. However, due to the absence of a centralized platform for AR gene resources, availability, consistency, and accuracy of information vary considerably across different databases. In this article, we explore existing AR gene data resources in order to make them more visible to the clinical microbiology community, to identify their limitations, and to propose potential solutions.
U2 - 10.1128/JCM.02717-15
DO - 10.1128/JCM.02717-15
M3 - Journal article
C2 - 26818666
VL - 54
SP - 851
EP - 859
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 4
ER -