Consolidating and Exploring Antibiotic Resistance Gene Data Resources

Basil Britto Xavier, Anupam J. Das, Guy Cochrane, Sandra De Ganck, Samir Kumar-Singh, Frank Møller Aarestrup, Herman Goossens, Surbhi Malhotra-Kumar

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The unrestricted use of antibiotics has resulted in rapid acquisition of antibiotic resistance (AR) and spread of multidrug-resistant (MDR) bacterial pathogens. With the advent of next-generation sequencing technologies and their application in understanding MDR pathogen dynamics, it has become imperative to unify AR gene data resources for easy accessibility for researchers. However, due to the absence of a centralized platform for AR gene resources, availability, consistency, and accuracy of information vary considerably across different databases. In this article, we explore existing AR gene data resources in order to make them more visible to the clinical microbiology community, to identify their limitations, and to propose potential solutions.
Original languageEnglish
JournalJournal of Clinical Microbiology
Volume54
Issue number4
Pages (from-to)851-859
Number of pages9
ISSN0095-1137
DOIs
Publication statusPublished - 2016

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