TY - JOUR
T1 - Confirmatory analysis of steroids in muscle using liquid chromatography-tandem mass spectrometry
AU - Pedersen, Mikael
AU - Andersen, Jens Hinge
PY - 2011
Y1 - 2011
N2 - A method is described for screening and confirmation of synthetic and endogenous steroids in muscle tissue. The method is sensitive, selective, and rapid and the consumption of organic solvents is low, compared to previously published methods. The procedure involves hydrolysis, defattening with heptane and final clean up with SPE using C18 cartridge. After filtration, the analytes are analysed by LC/MS/MS and quantification is performed using deuterated internal standards. Decision limits (CCα) varied from 0.02 to 0.33 μg kg-1 and the detection capabilities (CCβ) were
AB - A method is described for screening and confirmation of synthetic and endogenous steroids in muscle tissue. The method is sensitive, selective, and rapid and the consumption of organic solvents is low, compared to previously published methods. The procedure involves hydrolysis, defattening with heptane and final clean up with SPE using C18 cartridge. After filtration, the analytes are analysed by LC/MS/MS and quantification is performed using deuterated internal standards. Decision limits (CCα) varied from 0.02 to 0.33 μg kg-1 and the detection capabilities (CCβ) were
U2 - 10.1080/19440049.2010.549153
DO - 10.1080/19440049.2010.549153
M3 - Journal article
SN - 0265-203X
VL - 28
SP - 428
EP - 437
JO - Food Additives and Contaminants
JF - Food Additives and Contaminants
IS - 4
ER -