Confirmation that pulse and continuous peracetic acid administration does not disrupt the acute stress response in rainbow trout

Manuel Gesto*, Dibo Liu, Lars-Flemming Pedersen, Thomas Meinelt, David L. Strauss, Alfred Jokumsen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

Peracetic acid (PAA) is considered an eco-friendly alternative to other antimicrobial agents of common use in aquaculture. The literature suggests that fish can habituate to PAA exposure based on a reduction of the fish
corticosteroid response to PAA administration after repeated exposures. If that is true, PAA would also be a good option from the point of view of fish physiology. However, stronger evidence is needed to confirm that the use of PAA is welfare-friendly to fish. Besides habituation, other hypothetical factors such as desensitization, physiological exhaustion or PAA-mediated endocrine disruption could potentially explain the reduction in the corticosteroid response after repeated/prolonged PAA exposure. In this study, rainbow trout that had been exposed to PAA for several weeks were challenged with a secondary chasing stressor: fish were pursued with a dipnet for 1 min and their acute response was evaluated by measuring plasma cortisol, plasma glucose, plasma
lactate and brain serotonergic activity. All fish were equally able to mount a normal physiological stress response to the secondary stressor independent of previous exposure to PAA. This suggests that the decrease in the cortisol response after repeated exposure to PAA, as seen in previous studies, is a true habituation to PAA administration, which supports the use of PAA as a welfare-friendly antimicrobial agent in aquaculture
Original languageEnglish
JournalAquaculture
Volume492
Pages (from-to)190-194
ISSN0044-8486
DOIs
Publication statusPublished - 2018

Cite this

@article{2dba8b643a73448f8618489c70c27e60,
title = "Confirmation that pulse and continuous peracetic acid administration does not disrupt the acute stress response in rainbow trout",
abstract = "Peracetic acid (PAA) is considered an eco-friendly alternative to other antimicrobial agents of common use in aquaculture. The literature suggests that fish can habituate to PAA exposure based on a reduction of the fishcorticosteroid response to PAA administration after repeated exposures. If that is true, PAA would also be a good option from the point of view of fish physiology. However, stronger evidence is needed to confirm that the use of PAA is welfare-friendly to fish. Besides habituation, other hypothetical factors such as desensitization, physiological exhaustion or PAA-mediated endocrine disruption could potentially explain the reduction in the corticosteroid response after repeated/prolonged PAA exposure. In this study, rainbow trout that had been exposed to PAA for several weeks were challenged with a secondary chasing stressor: fish were pursued with a dipnet for 1 min and their acute response was evaluated by measuring plasma cortisol, plasma glucose, plasmalactate and brain serotonergic activity. All fish were equally able to mount a normal physiological stress response to the secondary stressor independent of previous exposure to PAA. This suggests that the decrease in the cortisol response after repeated exposure to PAA, as seen in previous studies, is a true habituation to PAA administration, which supports the use of PAA as a welfare-friendly antimicrobial agent in aquaculture",
author = "Manuel Gesto and Dibo Liu and Lars-Flemming Pedersen and Thomas Meinelt and Strauss, {David L.} and Alfred Jokumsen",
year = "2018",
doi = "10.1016/j.aquaculture.2018.04.009",
language = "English",
volume = "492",
pages = "190--194",
journal = "Aquaculture",
issn = "0044-8486",
publisher = "Elsevier",

}

Confirmation that pulse and continuous peracetic acid administration does not disrupt the acute stress response in rainbow trout. / Gesto, Manuel; Liu, Dibo; Pedersen, Lars-Flemming; Meinelt, Thomas; Strauss, David L.; Jokumsen, Alfred.

In: Aquaculture, Vol. 492, 2018, p. 190-194.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Confirmation that pulse and continuous peracetic acid administration does not disrupt the acute stress response in rainbow trout

AU - Gesto, Manuel

AU - Liu, Dibo

AU - Pedersen, Lars-Flemming

AU - Meinelt, Thomas

AU - Strauss, David L.

AU - Jokumsen, Alfred

PY - 2018

Y1 - 2018

N2 - Peracetic acid (PAA) is considered an eco-friendly alternative to other antimicrobial agents of common use in aquaculture. The literature suggests that fish can habituate to PAA exposure based on a reduction of the fishcorticosteroid response to PAA administration after repeated exposures. If that is true, PAA would also be a good option from the point of view of fish physiology. However, stronger evidence is needed to confirm that the use of PAA is welfare-friendly to fish. Besides habituation, other hypothetical factors such as desensitization, physiological exhaustion or PAA-mediated endocrine disruption could potentially explain the reduction in the corticosteroid response after repeated/prolonged PAA exposure. In this study, rainbow trout that had been exposed to PAA for several weeks were challenged with a secondary chasing stressor: fish were pursued with a dipnet for 1 min and their acute response was evaluated by measuring plasma cortisol, plasma glucose, plasmalactate and brain serotonergic activity. All fish were equally able to mount a normal physiological stress response to the secondary stressor independent of previous exposure to PAA. This suggests that the decrease in the cortisol response after repeated exposure to PAA, as seen in previous studies, is a true habituation to PAA administration, which supports the use of PAA as a welfare-friendly antimicrobial agent in aquaculture

AB - Peracetic acid (PAA) is considered an eco-friendly alternative to other antimicrobial agents of common use in aquaculture. The literature suggests that fish can habituate to PAA exposure based on a reduction of the fishcorticosteroid response to PAA administration after repeated exposures. If that is true, PAA would also be a good option from the point of view of fish physiology. However, stronger evidence is needed to confirm that the use of PAA is welfare-friendly to fish. Besides habituation, other hypothetical factors such as desensitization, physiological exhaustion or PAA-mediated endocrine disruption could potentially explain the reduction in the corticosteroid response after repeated/prolonged PAA exposure. In this study, rainbow trout that had been exposed to PAA for several weeks were challenged with a secondary chasing stressor: fish were pursued with a dipnet for 1 min and their acute response was evaluated by measuring plasma cortisol, plasma glucose, plasmalactate and brain serotonergic activity. All fish were equally able to mount a normal physiological stress response to the secondary stressor independent of previous exposure to PAA. This suggests that the decrease in the cortisol response after repeated exposure to PAA, as seen in previous studies, is a true habituation to PAA administration, which supports the use of PAA as a welfare-friendly antimicrobial agent in aquaculture

U2 - 10.1016/j.aquaculture.2018.04.009

DO - 10.1016/j.aquaculture.2018.04.009

M3 - Journal article

VL - 492

SP - 190

EP - 194

JO - Aquaculture

JF - Aquaculture

SN - 0044-8486

ER -