The Editorial Advisory Board of the Journal has assessed the papers published in Volume 33 by means of a three stage process of nomination and balloting. We are pleased to announce that the 2009 Best Paper of the Year Award goes to J.M. Harrold and R.S. Parker for their paper entitled “Clinically relevant cancer chemotherapy dose scheduling via mixed-integer optimization” (Vol. 33, Issue 12, 2042–2054, 2009). Our hearty congratulations to the co-authors!