Abstract
Combining the physical disector principle with an algorithm for automatic non-linear alignment of disector pairs we have developed a software system for direct measurement of 3D connectivity densities in iliac crest bone biopsies. The method was applied to biopsies from 14 non-selected autopsy cases: 7 men (age range 20-84 yr) and 7 women (age range 20-86 yr). The study reveals decreases in both trabecular bone mass and connectivity density with age in women.
| Original language | English |
|---|---|
| Journal | Mathematics and Computers in Simulation |
| Volume | 40 |
| Issue number | 3-4 |
| Pages (from-to) | 411-423 |
| ISSN | 0378-4754 |
| DOIs | |
| Publication status | Published - 1996 |
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