Abstract
Combining the physical disector principle with an algorithm for automatic non-linear alignment of disector pairs we have developed a software system for direct measurement of 3D connectivity densities in iliac crest bone biopsies. The method was applied to biopsies from 14 non-selected autopsy cases: 7 men (age range 20-84 yr) and 7 women (age range 20-86 yr). The study reveals decreases in both trabecular bone mass and connectivity density with age in women.
Original language | English |
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Journal | Mathematics and Computers in Simulation |
Volume | 40 |
Issue number | 3-4 |
Pages (from-to) | 411-423 |
ISSN | 0378-4754 |
DOIs | |
Publication status | Published - 1996 |