Compounds having pseudomonas anti-biofilm properties

Michael Givskov (Inventor), Tim Tolker-Nielsen (Inventor), Jens Andersen (Inventor), Tim Holm-Jakobsen (Inventor), Louise Hultqvist (Inventor), Carl Nilsson (Inventor), Thomas Nielsen (Inventor), Katrine Qvortrup (Inventor)

Research output: Patent

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Abstract

The present invention relates to c-di-GMP lowering chemical compounds having anti- biofilm properties. In particular, the present invention relates to anti-biofilm compounds or salts or tautomers thereof for use in treatment and/or prevention of bacterial biofilm infection in human subjects caused by biofilm-forming bacteria of the genus Pseudomonas, in particular Pseudomonas spp. including P. aeruginosa. Methods of treating such infections in human subjects are contemplated as well. The present inventions further relates to the use of an anti-biofilm compound or a salt or tautomer thereof for dispersing biofilms in industrial water systems.

Original languageEnglish
IPCC07D 401/ 04 A I
Patent numberWO2022043503
Filing date27/08/2020
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date27/08/2020
Priority numberEP20200193050
Publication statusPublished - 3 Mar 2022

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