Compositions comprising enzyme cleavable linker platforms and conjugates thereof

Katrine Qvortrup; Anders Højgaard Hansen; Katja Egeskov Grier; Amalie Nørskov

Compositions comprising enzyme cleavable linker platforms and conjugates thereof

Katrine Qvortrup (Inventor), Anders Højgaard Hansen (Inventor), Katja Egeskov Grier (Inventor), Amalie Nørskov (Inventor)

Department of Chemistry

Research output: Patent

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Abstract

The present invention relates to a cleavable linker platform. In particular, the invention relates to construction of an enzyme cleavable linker platform conjugated to a drug or a diagnostically relevant compound, a biomolecule, and an enzyme cleavable group, for which cleavage of the enzyme cleavable group leads to release of the drug or diagnostically relevant compound.

Original language	English
IPC	A61P 35/ 00 A I
Patent number	WO2020260597
Filing date	26/06/2019
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	26/06/2019
Priority number	EP20190182641
Publication status	Published - 30 Dec 2020

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AU - Qvortrup, Katrine

AU - Hansen, Anders Højgaard

AU - Grier, Katja Egeskov

AU - Nørskov, Amalie

PY - 2020/12/30

Y1 - 2020/12/30

N2 - The present invention relates to a cleavable linker platform. In particular, the invention relates to construction of an enzyme cleavable linker platform conjugated to a drug or a diagnostically relevant compound, a biomolecule, and an enzyme cleavable group, for which cleavage of the enzyme cleavable group leads to release of the drug or diagnostically relevant compound.

AB - The present invention relates to a cleavable linker platform. In particular, the invention relates to construction of an enzyme cleavable linker platform conjugated to a drug or a diagnostically relevant compound, a biomolecule, and an enzyme cleavable group, for which cleavage of the enzyme cleavable group leads to release of the drug or diagnostically relevant compound.

M3 - Patent

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Y2 - 2019/06/26

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Compositions comprising enzyme cleavable linker platforms and conjugates thereof

Abstract

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