Compositions and methods for modeling Saccharomyces cerevisiae metabolism

Bernard Palsson; Imandokht Famili; Pengcheng Fu; Jens B. Nielsen; Jochen Förster

Compositions and methods for modeling Saccharomyces cerevisiae metabolism

Bernard Palsson (Inventor)
, Imandokht Famili (Inventor)
, Pengcheng Fu (Inventor)
, Jens B. Nielsen (Inventor)
, Jochen Förster (Inventor)

Research output: Patent

310 Downloads (Orbit)

Abstract

The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention. The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.

Original language	English
IPC	G01N33/48; G06F17/30; G06F19/00
Patent number	WO03036296
Filing date	13/06/2012
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	26/10/2001
Priority number	US20010344447P
Publication status	Published - 2012

Bibliographical note

Also published as: WO03036296 (A1); WO03036296 (A9); US2010280803 (A1); US8170852 (B2); US2003228567 (A1); US7751981 (B2); JP2012164338 (A); JP2009187562 (A); JP5081187 (B2); JP2005507108 (A); EP2434421 (A2); EP2434421 (A3); EP1438580 (A1); EP1438580 (A4); CA2462099 (A1); CA2462099 (C); AU2002348089 (B2)

Access to Document

EP2463654A1Final published version, 5.43 MB

OpenUrl availability

Check availability in DTU Findit

Cite this

@misc{fe4e6ec851214c9b98bd4861e72234a9,

title = "Compositions and methods for modeling Saccharomyces cerevisiae metabolism",

abstract = "The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention. The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.",

author = "Bernard Palsson and Imandokht Famili and Pengcheng Fu and Nielsen, \{Jens B.\} and Jochen F{\"o}rster",

note = "Also published as: WO03036296 (A1); WO03036296 (A9); US2010280803 (A1); US8170852 (B2); US2003228567 (A1); US7751981 (B2); JP2012164338 (A); JP2009187562 (A); JP5081187 (B2); JP2005507108 (A); EP2434421 (A2); EP2434421 (A3); EP1438580 (A1); EP1438580 (A4); CA2462099 (A1); CA2462099 (C); AU2002348089 (B2) ; WO03036296; G01N33/48; G06F17/30; G06F19/00",

year = "2012",

language = "English",

type = "Patent",

}

TY - PAT

T1 - Compositions and methods for modeling Saccharomyces cerevisiae metabolism

AU - Palsson, Bernard

AU - Famili, Imandokht

AU - Fu, Pengcheng

AU - Nielsen, Jens B.

AU - Förster, Jochen

N1 - Also published as: WO03036296 (A1); WO03036296 (A9); US2010280803 (A1); US8170852 (B2); US2003228567 (A1); US7751981 (B2); JP2012164338 (A); JP2009187562 (A); JP5081187 (B2); JP2005507108 (A); EP2434421 (A2); EP2434421 (A3); EP1438580 (A1); EP1438580 (A4); CA2462099 (A1); CA2462099 (C); AU2002348089 (B2)

PY - 2012

Y1 - 2012

N2 - The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention. The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.

AB - The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention. The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.

M3 - Patent

M1 - WO03036296

Y2 - 2012/06/13

ER -

Compositions and methods for modeling Saccharomyces cerevisiae metabolism

Abstract

Bibliographical note

Access to Document

OpenUrl availability

Fingerprint

Cite this