Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)

Cihan Göksu; Lars G.  Hanson; Hartwig Siebner; Philipp Ehses; Klaus Scheffler; Axel Thielscher

Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)

Cihan Göksu
, Lars G. Hanson
, Hartwig Siebner
, Philipp Ehses
, Klaus Scheffler
, Axel Thielscher

Copenhagen University Hospital Herlev and Gentofte
University of Tübingen

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

198 Downloads (Orbit)

Abstract

MRCDI is a novel technique, utilizing dierent phase-sensitive MR methods for non-invasive measurements of weak currents in the human body, which is important in several neuroscience applications. Here, we compare the in-vivo performance of two dierent MR methods, multi-echo spin echo (MESE) and steady-state free precession free induction decay (SSFP-FID), with single- vs. multi-gradient-echo readouts. We demonstrate that multi-gradient-echo readouts improve both methods. We validate the linear dependence of the measured current-induced magnetic eld on the injected current strength for both methods, and propose the more ecient
SSFP-FID method as being well suited for highly sensitive single-slice human in-vivo MRCDI.

Original language	English
Publication date	2018
Number of pages	4
Publication status	Published - 2018
Event	Joint Annual Meeting ISMRM-ESMRMB 2018 - Paris Expo Porte de Versailles, Paris, France Duration: 16 Jun 2018 → 21 Jun 2018 https://www.ismrm.org/18m/

Conference

Conference	Joint Annual Meeting ISMRM-ESMRMB 2018
Location	Paris Expo Porte de Versailles
Country/Territory	France
City	Paris
Period	16/06/2018 → 21/06/2018
Internet address	https://www.ismrm.org/18m/

Access to Document

ISMRM18 5607 CihanSeqsFinal published version, 348 KB

OpenUrl availability

Check availability in DTU Findit

Cite this

@conference{a5f41ec10d4244b095b22e8554a36521,

title = "Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)",

abstract = "MRCDI is a novel technique, utilizing dierent phase-sensitive MR methods for non-invasive measurements of weak currents in the human body, which is important in several neuroscience applications. Here, we compare the in-vivo performance of two dierent MR methods, multi-echo spin echo (MESE) and steady-state free precession free induction decay (SSFP-FID), with single- vs. multi-gradient-echo readouts. We demonstrate that multi-gradient-echo readouts improve both methods. We validate the linear dependence of the measured current-induced magnetic eld on the injected current strength for both methods, and propose the more ecient SSFP-FID method as being well suited for highly sensitive single-slice human in-vivo MRCDI.",

author = "Cihan G{\"o}ksu and Hanson, \{Lars G.\} and Hartwig Siebner and Philipp Ehses and Klaus Scheffler and Axel Thielscher",

year = "2018",

language = "English",

note = "Joint Annual Meeting ISMRM-ESMRMB 2018 ; Conference date: 16-06-2018 Through 21-06-2018",

url = "https://www.ismrm.org/18m/",

}

TY - ABST

T1 - Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)

AU - Göksu, Cihan

AU - Hanson, Lars G.

AU - Siebner, Hartwig

AU - Ehses, Philipp

AU - Scheffler, Klaus

AU - Thielscher, Axel

PY - 2018

Y1 - 2018

N2 - MRCDI is a novel technique, utilizing dierent phase-sensitive MR methods for non-invasive measurements of weak currents in the human body, which is important in several neuroscience applications. Here, we compare the in-vivo performance of two dierent MR methods, multi-echo spin echo (MESE) and steady-state free precession free induction decay (SSFP-FID), with single- vs. multi-gradient-echo readouts. We demonstrate that multi-gradient-echo readouts improve both methods. We validate the linear dependence of the measured current-induced magnetic eld on the injected current strength for both methods, and propose the more ecient SSFP-FID method as being well suited for highly sensitive single-slice human in-vivo MRCDI.

AB - MRCDI is a novel technique, utilizing dierent phase-sensitive MR methods for non-invasive measurements of weak currents in the human body, which is important in several neuroscience applications. Here, we compare the in-vivo performance of two dierent MR methods, multi-echo spin echo (MESE) and steady-state free precession free induction decay (SSFP-FID), with single- vs. multi-gradient-echo readouts. We demonstrate that multi-gradient-echo readouts improve both methods. We validate the linear dependence of the measured current-induced magnetic eld on the injected current strength for both methods, and propose the more ecient SSFP-FID method as being well suited for highly sensitive single-slice human in-vivo MRCDI.

M3 - Conference abstract for conference

T2 - Joint Annual Meeting ISMRM-ESMRMB 2018

Y2 - 16 June 2018 through 21 June 2018

ER -

Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)

Abstract

Conference

Access to Document

OpenUrl availability

Fingerprint

Cite this