Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)

Cihan Göksu, Lars G. Hanson, Hartwig Siebner, Philipp Ehses, Klaus Scheffler, Axel Thielscher

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MRCDI is a novel technique, utilizing dierent phase-sensitive MR methods for non-invasive measurements of weak currents in the human body, which is important in several neuroscience applications. Here, we compare the in-vivo performance of two dierent MR methods, multi-echo spin echo (MESE) and steady-state free precession free induction decay (SSFP-FID), with single- vs. multi-gradient-echo readouts. We demonstrate that multi-gradient-echo readouts improve both methods. We validate the linear dependence of the measured current-induced magnetic eld on the injected current strength for both methods, and propose the more ecient
SSFP-FID method as being well suited for highly sensitive single-slice human in-vivo MRCDI.
Original languageEnglish
Publication date2018
Number of pages4
Publication statusPublished - 2018
EventJoint Annual Meeting ISMRM-ESMRMB 2018 - Paris Expo Porte de Versailles, Paris, France
Duration: 16 Jun 201821 Jun 2018


ConferenceJoint Annual Meeting ISMRM-ESMRMB 2018
LocationParis Expo Porte de Versailles
Internet address

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