Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe

Pablo Alarcon; Adam Brouwer; Divya Venkatesh; Daisy Duncan; Chrysostomos I. Dovas; George Georgiades; Isabella Monne; Alice Fusaro; Adam Dan; Krzysztof Smietanka; Vassilios Ragias; Andrew C. Breed; Taxiarchis Chassalevris; Gabriela Goujgoulova; Charlotte Kristiane Hjulsager; Eoin Ryan; Azucena Sanchez; Eric Niqueux; Niina Tammiranta; Siamak Zohari; David A. Stroud; Vladimir Savic; Nicola S. Lewis; Ian H. Brown

doi:10.3201/eid2412.171860

Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe

Pablo Alarcon
, Adam Brouwer^*
, Divya Venkatesh
, Daisy Duncan
, Chrysostomos I. Dovas
, George Georgiades
, Isabella Monne
, Alice Fusaro
, Adam Dan
, Krzysztof Smietanka
, Vassilios Ragias
, Andrew C. Breed
, Taxiarchis Chassalevris
, Gabriela Goujgoulova
, Charlotte Kristiane Hjulsager
, Eoin Ryan
, Azucena Sanchez
, Eric Niqueux
, Niina Tammiranta
, Siamak Zohari

David A. Stroud, Vladimir Savic, Nicola S. Lewis, Ian H. Brown

^*Corresponding author for this work

Animal & Plant Health Agency
University of Cambridge
Aristotle University of Thessaloniki
Ministry of Rural Development and Food
Instituto Zooprofilattico Sperimentale delle Venezie
Veterinary Diagnostic Institute
National Veterinary Research Institute
University of Queensland
NDRVMI
Central Veterinary Research Laboratory
Central Veterinary Laboratory
Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail
Finnish Food Safety Authority
National Veterinary Institute
Joint Nature Conservation Committee
Croatian Veterinary Institute

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Abstract

We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest diversity of wild birds infected. We observed significant differences among the 3 epizootics regarding region affected, epidemic curve, seasonality, and outbreak duration, making it difficult to predict future HPAI epizootics. However, we know that in 2005-06 and 2016-17 the initial peak of wild bird detections preceded the peak of poultry outbreaks within Europe. Phylogenetic analysis of 2016-17 viruses indicates 2 main pathways into Europe. Our findings highlight the need for global surveillance of viral changes to inform disease preparedness, detection, and control.

Original language	English
Journal	Emerging Infectious Diseases
Volume	24
Issue number	12
Pages (from-to)	2270-2283
ISSN	1080-6040
DOIs	https://doi.org/10.3201/eid2412.171860
Publication status	Published - 2018

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Alarcon, P., Brouwer, A., Venkatesh, D., Duncan, D., Dovas, C. I., Georgiades, G., Monne, I., Fusaro, A., Dan, A., Smietanka, K., Ragias, V., Breed, A. C., Chassalevris, T., Goujgoulova, G., Hjulsager, C. K., Ryan, E., Sanchez, A., Niqueux, E., Tammiranta, N., ... Brown, I. H. (2018). Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe. Emerging Infectious Diseases , 24(12), 2270-2283. https://doi.org/10.3201/eid2412.171860

@article{6cab1b3738364fb09b2132bea9cf1d1e,

title = "Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe",

abstract = "We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest diversity of wild birds infected. We observed significant differences among the 3 epizootics regarding region affected, epidemic curve, seasonality, and outbreak duration, making it difficult to predict future HPAI epizootics. However, we know that in 2005-06 and 2016-17 the initial peak of wild bird detections preceded the peak of poultry outbreaks within Europe. Phylogenetic analysis of 2016-17 viruses indicates 2 main pathways into Europe. Our findings highlight the need for global surveillance of viral changes to inform disease preparedness, detection, and control.",

author = "Pablo Alarcon and Adam Brouwer and Divya Venkatesh and Daisy Duncan and Dovas, \{Chrysostomos I.\} and George Georgiades and Isabella Monne and Alice Fusaro and Adam Dan and Krzysztof Smietanka and Vassilios Ragias and Breed, \{Andrew C.\} and Taxiarchis Chassalevris and Gabriela Goujgoulova and Hjulsager, \{Charlotte Kristiane\} and Eoin Ryan and Azucena Sanchez and Eric Niqueux and Niina Tammiranta and Siamak Zohari and Stroud, \{David A.\} and Vladimir Savic and Lewis, \{Nicola S.\} and Brown, \{Ian H.\}",

year = "2018",

doi = "10.3201/eid2412.171860",

language = "English",

volume = "24",

pages = "2270--2283",

journal = "Emerging Infectious Diseases ",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "12",

}

Alarcon, P, Brouwer, A, Venkatesh, D, Duncan, D, Dovas, CI, Georgiades, G, Monne, I, Fusaro, A, Dan, A, Smietanka, K, Ragias, V, Breed, AC, Chassalevris, T, Goujgoulova, G, Hjulsager, CK, Ryan, E, Sanchez, A, Niqueux, E, Tammiranta, N, Zohari, S, Stroud, DA, Savic, V, Lewis, NS & Brown, IH 2018, 'Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe', Emerging Infectious Diseases , vol. 24, no. 12, pp. 2270-2283. https://doi.org/10.3201/eid2412.171860

TY - JOUR

T1 - Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe

AU - Alarcon, Pablo

AU - Brouwer, Adam

AU - Venkatesh, Divya

AU - Duncan, Daisy

AU - Dovas, Chrysostomos I.

AU - Georgiades, George

AU - Monne, Isabella

AU - Fusaro, Alice

AU - Dan, Adam

AU - Smietanka, Krzysztof

AU - Ragias, Vassilios

AU - Breed, Andrew C.

AU - Chassalevris, Taxiarchis

AU - Goujgoulova, Gabriela

AU - Hjulsager, Charlotte Kristiane

AU - Ryan, Eoin

AU - Sanchez, Azucena

AU - Niqueux, Eric

AU - Tammiranta, Niina

AU - Zohari, Siamak

AU - Stroud, David A.

AU - Savic, Vladimir

AU - Lewis, Nicola S.

AU - Brown, Ian H.

PY - 2018

Y1 - 2018

N2 - We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest diversity of wild birds infected. We observed significant differences among the 3 epizootics regarding region affected, epidemic curve, seasonality, and outbreak duration, making it difficult to predict future HPAI epizootics. However, we know that in 2005-06 and 2016-17 the initial peak of wild bird detections preceded the peak of poultry outbreaks within Europe. Phylogenetic analysis of 2016-17 viruses indicates 2 main pathways into Europe. Our findings highlight the need for global surveillance of viral changes to inform disease preparedness, detection, and control.

AB - We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest diversity of wild birds infected. We observed significant differences among the 3 epizootics regarding region affected, epidemic curve, seasonality, and outbreak duration, making it difficult to predict future HPAI epizootics. However, we know that in 2005-06 and 2016-17 the initial peak of wild bird detections preceded the peak of poultry outbreaks within Europe. Phylogenetic analysis of 2016-17 viruses indicates 2 main pathways into Europe. Our findings highlight the need for global surveillance of viral changes to inform disease preparedness, detection, and control.

U2 - 10.3201/eid2412.171860

DO - 10.3201/eid2412.171860

M3 - Journal article

C2 - 30457528

SN - 1080-6040

VL - 24

SP - 2270

EP - 2283

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 12

ER -

Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe

Abstract

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