Combining aptamers and in silico interaction studies to decipher the function of hypothetical proteins

Prashanth  Suravajhala; Harsha Vardhan Reddy Burri; Arto Heiskanen

Combining aptamers and in silico interaction studies to decipher the function of hypothetical proteins

Prashanth Suravajhala
, Harsha Vardhan Reddy Burri
, Arto Heiskanen

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Abstract

We present the potential role of aptamers in elucidating the function of hypothetical proteins, as well as the possibilities provided by bioinformatics for establishing a benchmark for aptamer-protein prediction methods. With these future perspectives, the role of hypothetical proteins as target molecules for diagnostics and therapies could prove to be very useful in development of medical technology.

Original language	English
Journal	European Chemical Bulletin
Volume	3
Issue number	8
Pages (from-to)	809-810
ISSN	2063-5346
Publication status	Published - 2014

Keywords

Aptamers
Hypothetical proteins
Pull down assay
In silico studies

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COMBINING APTAMERS AND IN SILICO INTERACTION STUDIES TO DECIPHER THE FUNCTION OF HYPOTHETICAL PROTEINSFinal published version, 30.1 KB

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abstract = "We present the potential role of aptamers in elucidating the function of hypothetical proteins, as well as the possibilities provided by bioinformatics for establishing a benchmark for aptamer-protein prediction methods. With these future perspectives, the role of hypothetical proteins as target molecules for diagnostics and therapies could prove to be very useful in development of medical technology.",

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AU - Burri, Harsha Vardhan Reddy

AU - Heiskanen, Arto

PY - 2014

Y1 - 2014

N2 - We present the potential role of aptamers in elucidating the function of hypothetical proteins, as well as the possibilities provided by bioinformatics for establishing a benchmark for aptamer-protein prediction methods. With these future perspectives, the role of hypothetical proteins as target molecules for diagnostics and therapies could prove to be very useful in development of medical technology.

AB - We present the potential role of aptamers in elucidating the function of hypothetical proteins, as well as the possibilities provided by bioinformatics for establishing a benchmark for aptamer-protein prediction methods. With these future perspectives, the role of hypothetical proteins as target molecules for diagnostics and therapies could prove to be very useful in development of medical technology.

KW - Aptamers

KW - Hypothetical proteins

KW - Pull down assay

KW - In silico studies

M3 - Journal article

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JO - European Chemical Bulletin

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Combining aptamers and in silico interaction studies to decipher the function of hypothetical proteins

Abstract

Keywords

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