Combinatorial Solid-Phase Synthesis of Balanol Analogues

John Nielsen; Lars Ole Lyngsø

doi:10.1016/0040-4039(96)01913-2

Combinatorial Solid-Phase Synthesis of Balanol Analogues

John Nielsen, Lars Ole Lyngsø

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

The natural product balanol has served as a template for the design and synthesis of a combinatorial library using solid-phase chemistry. Using a retrosynthetic analysis, the structural analogues have been assembled from three relatively accessible building blocks. The solid-phase chemistry including MSNT-mediated esterification of both support-bound alcohols and carboxylic acids has been implemented successfully. Copyright (C) 1996 Elsevier Science Ltd.

Original language	English
Journal	Tetrahedron Letters
Volume	37
Issue number	46
Pages (from-to)	8439-8442
ISSN	0040-4039
DOIs	https://doi.org/10.1016/0040-4039(96)01913-2
Publication status	Published - 1996

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title = "Combinatorial Solid-Phase Synthesis of Balanol Analogues",

abstract = "The natural product balanol has served as a template for the design and synthesis of a combinatorial library using solid-phase chemistry. Using a retrosynthetic analysis, the structural analogues have been assembled from three relatively accessible building blocks. The solid-phase chemistry including MSNT-mediated esterification of both support-bound alcohols and carboxylic acids has been implemented successfully. Copyright (C) 1996 Elsevier Science Ltd.",

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AU - Lyngsø, Lars Ole

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AB - The natural product balanol has served as a template for the design and synthesis of a combinatorial library using solid-phase chemistry. Using a retrosynthetic analysis, the structural analogues have been assembled from three relatively accessible building blocks. The solid-phase chemistry including MSNT-mediated esterification of both support-bound alcohols and carboxylic acids has been implemented successfully. Copyright (C) 1996 Elsevier Science Ltd.

U2 - 10.1016/0040-4039(96)01913-2

DO - 10.1016/0040-4039(96)01913-2

M3 - Journal article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Combinatorial Solid-Phase Synthesis of Balanol Analogues

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